Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.65 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2141120 | 1.00 | LMNA (0.65) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL23340688 | 1.00 | LMNA (0.65) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL18219728 | 0.85 | ALDH1A1 (0.59) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL25983246 | 0.85 | LMNA (0.50) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL13225623 | 0.84 | KMT2A (0.59) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL5642554 | 0.83 | — | — | |
| SCHEMBL5610095 | 0.80 | CES2 (0.69) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL5610101 | 0.80 | CES2 (0.69) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL28465997 | 0.80 | CES2 (0.64) | LMNAL3MBTL1P4HTMNAPRTCES2 | |
| SCHEMBL2489302 | 0.80 | CES2 (0.64) | LMNAL3MBTL1P4HTMNAPRTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10017474-B1 | Method of synthesizing (E)-1,2-di(pyridin-2-yl) ethene-1,2-diol | KING SAUD UNIVERSITY (SA) | 2018-07-10 | — | — | US | claimed |
| EP-2025697-B1 | Process to obtain dimers, trimers and up to polymers from pyridinemethanol derivatives compounds | BENEMERITA UNIVERSIDAD AUTONOMA DE PUEBLA (MX) | 2013-12-18 | — | — | EP | claimed |
| US-20090043063-A1 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | PERCINO ZACARIAS, Maria Judith (MX) | 2009-02-12 | — | — | US | claimed |
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | QATAR UNIVERSITY (QA) | 2023-08-08 | — | — | US | disclosed |
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | QATAR UNIVERSITY (QA) | 2023-08-08 | — | — | US | disclosed |
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | QATAR UNIVERSITY (QA) | 2023-08-08 | — | — | US | disclosed |
| US-20220204487-A1 | ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST | QATAR UNIVERSITY (QA) | 2022-06-30 | — | — | US | disclosed |
| US-20220204487-A1 | ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST | QATAR UNIVERSITY (QA) | 2022-06-30 | — | — | US | disclosed |
| US-10017474-B1 | Method of synthesizing (E)-1,2-di(pyridin-2-yl) ethene-1,2-diol | KING SAUD UNIVERSITY (SA) | 2018-07-10 | — | — | US | disclosed |
| US-10017474-B1 | Method of synthesizing (E)-1,2-di(pyridin-2-yl) ethene-1,2-diol | KING SAUD UNIVERSITY (SA) | 2018-07-10 | — | — | US | disclosed |
| US-10017474-B1 | Method of synthesizing (E)-1,2-di(pyridin-2-yl) ethene-1,2-diol | KING SAUD UNIVERSITY (SA) | 2018-07-10 | — | — | US | disclosed |
| EP-2025697-B1 | Process to obtain dimers, trimers and up to polymers from pyridinemethanol derivatives compounds | BENEMERITA UNIVERSIDAD AUTONOMA DE PUEBLA (MX) | 2013-12-18 | — | — | EP | disclosed |
| US-7989583-B2 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | BENEMERITA UNIVERSIDAD AUTONOMA DE PUEBLA (MX) | 2011-08-02 | — | — | US | disclosed |
| US-7989583-B2 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | BENEMERITA UNIVERSIDAD AUTONOMA DE PUEBLA (MX) | 2011-08-02 | — | — | US | disclosed |
| US-7989583-B2 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | BENEMERITA UNIVERSIDAD AUTONOMA DE PUEBLA (MX) | 2011-08-02 | — | — | US | disclosed |
| EP-2025697-A1 | Process to obtain dimers, trimers and up to polymers from pyridinemethanol derivatives compounds | Benemerita Universidad Autonoma de Puebla (MX) | 2009-02-18 | — | — | EP | disclosed |
| EP-2025697-A1 | Process to obtain dimers, trimers and up to polymers from pyridinemethanol derivatives compounds | Benemerita Universidad Autonoma de Puebla (MX) | 2009-02-18 | — | — | EP | disclosed |
| US-20090043063-A1 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | PERCINO ZACARIAS, Maria Judith (MX) | 2009-02-12 | — | — | US | disclosed |
| US-20090043063-A1 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | PERCINO ZACARIAS, Maria Judith (MX) | 2009-02-12 | — | — | US | disclosed |
| US-20090043063-A1 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | PERCINO ZACARIAS, Maria Judith (MX) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718607-B2 | Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst | AP2A2, AP2A1, DNM2 | LMNA 4714/4885L3MBTL1 4181/4885P4HTM 4605/4885 |
| US-10017474-B1 | Method of synthesizing (E)-1,2-di(pyridin-2-yl) ethene-1,2-diol | DPYSL2, DPYD, RER1 | LMNA 1359/4885L3MBTL1 4225/4885P4HTM 786/4885 |
| US-20090043063-A1 | Process to obtain dimers, trimers and up to polymers from pyridinmethanol derivatives compounds | PNPO, ADH1A, CYP2E1 | LMNA 2020/4885L3MBTL1 4610/4885P4HTM 1009/4885 |
| US-20220204487-A1 | ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST | AP2A2, AP2A1, DNM2 | LMNA 4714/4885L3MBTL1 4181/4885P4HTM 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.