Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10742442 | 0.80 | MAPT (0.49) | ALDH1A1MAPK1KDM4EMAPTHPGD | |
| SCHEMBL7769015 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL25383926 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL30557573 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL10421946 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6408883 | 0.73 | CNR2 (0.44) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL8323182 | 0.73 | TUBB4A (0.48) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL144440 | 0.73 | GPR3 (0.55) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL10369586 | 0.72 | CA2 (0.49) | ALDH1A1MAPK1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL1098130 | 0.72 | MCL1 (0.57) | ALDH1A1MAPK1KDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111225907-B | Process for preparing benzothien-2 yl boric acid/borate | 拜耳制药股份公司 | 2023-05-26 | — | — | CN | disclosed |
| US-20220356194-A1 | PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-11-10 | — | — | US | disclosed |
| US-11274110-B2 | Process for preparing benzothiophen-2yl boronate | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-03-15 | — | — | US | disclosed |
| US-20200339606-A1 | PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-10-29 | — | — | US | disclosed |
| EP-3700894-A1 | PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE | Bayer Pharma Aktiengesellschaft (DE) | 2020-09-02 | — | — | EP | disclosed |
| CN-111225907-A | Process for preparing benzothien-2-yl boronic acids/borates | 拜耳制药股份公司 | 2020-06-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220356194-A1 | PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE | BPGM, BRCA1, BRAP | ALDH1A1 1918/4885MAPK1 1021/4885KDM4E 1509/4885 |
| US-20200339606-A1 | PROCESS FOR PREPARING BENZOTHIOPHEN-2YL BORONATE | BPGM, BRCA1, BRAP | ALDH1A1 1918/4885MAPK1 1021/4885KDM4E 1509/4885 |
| US-11274110-B2 | Process for preparing benzothiophen-2yl boronate | BPGM, BRCA1, BRAP | ALDH1A1 1918/4885MAPK1 1021/4885KDM4E 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.