Butyrolactone

Butyrolactone

SCHEMBL22367208

CC=C(C)C(=O)O.O=C1CCCO1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.48
CA9 Q16790 1/20 0.48
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL701741 0.93 CA1 (0.55) CA1CA9ALDH1A1LMNATP53
SCHEMBL701742 0.93 CA1 (0.55) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL10999881 0.84 CA1 (0.61) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL7650673 0.82 CA1 (0.64) CA1CA9ALDH1A1LMNATP53
Methacrylic Acid SCHEMBL212354 0.81 CA1 (0.52) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL25427151 0.80 CA1 (0.67) CA1CA9ALDH1A1LMNATP53
Butyrolactone SCHEMBL7686323 0.80 CA1 (0.67) CA1CA9ALDH1A1LMNATP53
Acetic Acid SCHEMBL28267793 0.78 CA1 (0.73) CA1CA9ALDH1A1LMNATP53
Crotonic Acid SCHEMBL27977237 0.78 CA1 (0.48) CA1CA9ALDH1A1LMNATP53
Bicarbonate SCHEMBL27877696 0.78 CA1 (0.59) CA1CA9ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220296512-A1 GEL FOR TREATING PERIOCULAR AND/OR ORBITAL PATHOLOGIES AND CONDITIONS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-09-22 US claimed
US-12296044-B2 Gel for treating periocular and/or orbital pathologies and conditions UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2025-05-13 US disclosed
US-12097260-B2 Temperature-responsive degradable hydrogels SONORAN BIOSCIENCES, INC. (US) 2024-09-24 US disclosed
US-20220296512-A1 GEL FOR TREATING PERIOCULAR AND/OR ORBITAL PATHOLOGIES AND CONDITIONS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-09-22 US disclosed
US-11382862-B2 Gel for treating periocular and/or orbital pathologies and conditions University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2022-07-12 US disclosed
US-20220072134-A1 TEMPERATURE-RESPONSIVE DEGRADABLE HYDROGELS SONORAN BIOSCIENCES, INC. (US) 2022-03-10 US disclosed
US-11173210-B2 Temperature-responsive degradable hydrogels SONORAN BIOSCIENCES, INC. (US) 2021-11-16 US disclosed
US-20200323987-A1 TEMPERATURE-RESPONSIVE DEGRADABLE HYDROGELS SONORAN BIOSCIENCES, INC. (US) 2020-10-15 US disclosed
EP-3700589-A1 TEMPERATURE-RESPONSIVE DEGRADABLE HYDROGELS Sonoran Biosciences, Inc. (US) 2020-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11382862-B2 Gel for treating periocular and/or orbital pathologies and conditions MMP13, ELANE, MMP1 CA1 4727/4885CA9 1858/4885ALDH1A1 1132/4885
US-20200323987-A1 TEMPERATURE-RESPONSIVE DEGRADABLE HYDROGELS LCT, DLST, ALG1 CA1 574/4885CA9 1123/4885ALDH1A1 1804/4885
US-12296044-B2 Gel for treating periocular and/or orbital pathologies and conditions MMP13, ELANE, MMP1 CA1 4727/4885CA9 1858/4885ALDH1A1 1132/4885
US-20220296512-A1 GEL FOR TREATING PERIOCULAR AND/OR ORBITAL PATHOLOGIES AND CONDITIONS MMP13, ELANE, MMP1 CA1 4727/4885CA9 1858/4885ALDH1A1 1132/4885
US-12097260-B2 Temperature-responsive degradable hydrogels LCT, DLST, ALG1 CA1 574/4885CA9 1123/4885ALDH1A1 1804/4885
US-20220072134-A1 TEMPERATURE-RESPONSIVE DEGRADABLE HYDROGELS LCT, DLST, ALG1 CA1 574/4885CA9 1123/4885ALDH1A1 1804/4885
US-11173210-B2 Temperature-responsive degradable hydrogels LCT, DLST, ALG1 CA1 574/4885CA9 1123/4885ALDH1A1 1804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.