Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22369876 | 0.81 | CDK1 (0.41) | SLC6A3SLC6A4SLC6A2MAOAMAOB | |
| SCHEMBL22369869 | 0.72 | ATF4 (0.39) | SLC6A3SLC6A4LMNAHTT | |
| SCHEMBL22369880 | 0.71 | MAOA (0.50) | SLC6A3SLC6A4SLC6A2MAOAMAOB | |
| Hydrochloric Acid SCHEMBL20565118 | 0.69 | MAOB (0.48) | SLC6A3SLC6A4SLC6A2MAOAMAOB | |
| SCHEMBL29525490 | 0.69 | RORC (0.41) | LMNAHTT | |
| SCHEMBL29525428 | 0.66 | APP (0.44) | MAOAMAOBKDM1AOPRM1OPRL1 | |
| SCHEMBL23141350 | 0.65 | KDM4E (0.51) | KMT2A | |
| SCHEMBL21322308 | 0.64 | GRIN2D (0.36) | — | |
| Hydrochloric Acid SCHEMBL20564400 | 0.62 | GRIN2D (0.35) | — | |
| SCHEMBL1797711 | 0.62 | KIF11 (0.52) | KIF11MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200270221-A1 | ANALGESIC COMPOUNDS | KTHERA, LLC | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270221-A1 | ANALGESIC COMPOUNDS | INA, IK, ACHE | SLC6A3 1919/4885SLC6A4 1670/4885SLC6A2 1838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.