SCHEMBL2238652

SCHEMBL2238652

CCCCC(=O)OC1C(=O)NC(=O)C1OC(=O)CCCC

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.47
NAAA Q02083 2/20 0.42
DGKA P23743 1/20 0.41
PRKCA P17252 6/20 0.40
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2239670 0.93 DGKA (0.52) LMNANAAADGKAPRKCA
SCHEMBL11206235 0.84 PRKCA (0.47) LMNANAAADGKAPRKCA
SCHEMBL2240258 0.76 NAAA (0.41) LMNANAAADGKAPRKCA
SCHEMBL5081024 0.71 NAAA (0.47) LMNANAAADGKAPRKCA
SCHEMBL6676582 0.71 PPARG (0.41) NAAAPRKCA
SCHEMBL3684117 0.71 NAAA (0.37) LMNANAAAPRKCA
SCHEMBL2099423 0.70 PRKCA (0.47) NAAADGKAPRKCA
SCHEMBL2238546 0.70 NAAA (0.50) LMNANAAADGKAPRKCA
SCHEMBL5079237 0.70 NAAA (0.50) LMNANAAADGKAPRKCA
SCHEMBL5080133 0.70 NAAA (0.50) LMNANAAADGKAPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994330-B2 Oxidizing p-xylene to terephthalic acid using a catalyst having a dicarboximide skeleton; hydrothermally treating the product with hot water, decomposing and removing catalyst impurities DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2011-08-09 US disclosed
US-20080171881-A1 Method for Producing Organic Compound and Method for Decomposing Compound Having Dicarboximide Skeleton DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2008-07-17 US disclosed
EP-1870394-A1 METHOD FOR PRODUCING ORGANIC COMPOUND AND METHOD FOR DECOMPOSING COMPOUND HAVING DICARBOXYIMIDE SKELETON Daicel Chemical Industries, Ltd. (JP) 2007-12-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171881-A1 Method for Producing Organic Compound and Method for Decomposing Compound Having Dicarboximide Skeleton DHPS, OGDH, MCCC2 LMNA 1905/4885NAAA 483/4885DGKA 948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.