Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | TNF | P01375 | 2/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | LTK | P29376 | 1/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | MST1R | Q04912 | 1/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30322772 | 1.00 | MAOA (0.47) | MAOAMAOBCYP19A1TNFPLK4 | |
| SCHEMBL11369963 | 0.89 | MAOA (0.50) | MAOAMAOBCYP19A1TNFPLK4 | |
| SCHEMBL29699898 | 0.89 | SIGMAR1 (0.48) | MAOAMAOBLMNAMAPTSMN1; SMN2 | |
| SCHEMBL14452876 | 0.89 | SIGMAR1 (0.48) | MAOAMAOBLMNAMAPTSMN1; SMN2 | |
| SCHEMBL23154411 | 0.88 | MAOA (0.67) | MAOAMAOBCYP19A1TNFKDM4E | |
| SCHEMBL19051940 | 0.88 | CYP19A1 (0.41) | MAOAMAOBCYP19A1TNFPLK4 | |
| SCHEMBL3075871 | 0.87 | MAOA (0.47) | MAOAMAOBCYP19A1TNFPLK4 | |
| SCHEMBL30322863 | 0.87 | MAOA (0.47) | MAOAMAOBCYP19A1TNFPLK4 | |
| SCHEMBL11559098 | 0.85 | MAOA (0.45) | MAOAMAOBCYP19A1TNFPLK4 | |
| SCHEMBL8618246 | 0.84 | SIGMAR1 (0.46) | MAOAMAOBCYP19A1TNFKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923387-B1 | ACYLGUANIDINE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2011-10-19 | — | — | EP | claimed |
| US-20100168096-A1 | ACYLGUANIDINE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-07-01 | — | — | US | claimed |
| EP-1923387-A1 | ACYLGUANIDINE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2008-05-21 | — | — | EP | claimed |
| EP-0698226-A4 | COMPLEMENTARY SURFACE CONFINED POLYMER ELECTROCHROMIC MATERIALS, SYSTEMS, AND METHODS OF FABRICATION THEREFOR | IGEN INC (US) | 1997-02-12 | — | — | EP | claimed |
| EP-0698226-A1 | COMPLEMENTARY SURFACE CONFINED POLYMER ELECTROCHROMIC MATERIALS, SYSTEMS, AND METHODS OF FABRICATION THEREFOR | IGEN, INCORPORATED (US) | 1996-02-28 | — | — | EP | claimed |
| US-11818949-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2023-11-14 | — | — | US | disclosed |
| US-20230157166-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | CANON KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
| US-20230131934-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-04-27 | — | — | US | disclosed |
| WO-2020125589-A1 | PHOSPHINE OXIDE GROUP-CONTAINED TRANSITION METAL COMPLEX, AND POLYMER, MIXTURE, COMPOSITION, AND ORGANIC ELECTRONIC DEVICE THEREOF | 广州华睿光电材料有限公司 | 2020-06-25 | — | — | WO | disclosed |
| EP-3242872-B1 | (PIPERIDIN-3-YL)(NAPHTHALEN-2-YL)METHANONE DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF THE HISTONE DEMETHYLASE KDM2B FOR THE TREATMENT OF CANCER | GENENTECH INC (US) | 2019-07-03 | — | — | EP | disclosed |
| US-20180226580-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2018-08-09 | — | — | US | disclosed |
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2018-07-26 | — | — | US | disclosed |
| US-5070100-A | COMPLICATIONS OF DIABETES | ALCON LABORATORIES, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-4864028-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0311010-A2 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1989-04-12 | — | — | EP | disclosed |
| US-4605660-A | INHIBIT CONTRACTION OF SMOOTH MUSCLE | MERCK & CO., INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4605660-A | INHIBIT CONTRACTION OF SMOOTH MUSCLE | MERCK & CO., INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4605660-A | INHIBIT CONTRACTION OF SMOOTH MUSCLE | MERCK & CO., INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4537892-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0137333-A2 | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase | ALCON LABORATORIES, INC. (US) | 1985-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180212158-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | MSN, DDT, NECTIN4 | MAOA 175/4885MAOB 55/4885CYP19A1 2096/4885 |
| US-20230131934-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | OCIAD1, OCIAD2, OSBP | MAOA 1466/4885MAOB 892/4885CYP19A1 2201/4885 |
| US-11818949-B2 | Organic electroluminescent materials and devices | EML4, TBCB, TERF2IP | MAOA 679/4885MAOB 284/4885CYP19A1 3908/4885 |
| US-20180226580-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SLCO4C1, SLCO2A1, SLCO2B1 | MAOA 1810/4885MAOB 910/4885CYP19A1 747/4885 |
| US-20230157166-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT | OR10J3, OR51E2, OLA1 | MAOA 1453/4885MAOB 773/4885CYP19A1 250/4885 |
| US-20100168096-A1 | ACYLGUANIDINE DERIVATIVE OR SALT THEREOF | HTR2B, HTR7, HTR3B | MAOA 553/4885MAOB 187/4885CYP19A1 2369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.