SCHEMBL3075871

SCHEMBL3075871

c1ccc2c(c1)Cc1ccncc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.47
MAOB P27338 1/20 0.47
CYP19A1 P11511 6/20 0.46
TNF P01375 2/20 0.46
PLK4 O00444 1/20 0.46
DAPK3 O43293 1/20 0.46
PIM1 P11309 1/20 0.46
PDGFRA P16234 1/20 0.46
LTK P29376 1/20 0.46
MAP2K2 P36507 1/20 0.46
FLT3 P36888 1/20 0.46
MAPK8 P45983 1/20 0.46
MAPK9 P45984 1/20 0.46
CSNK1A1 P48729 1/20 0.46
TDO2 P48775 1/20 0.46
CDK8 P49336 1/20 0.46
CDK5 Q00535 1/20 0.46
MAP2K1 Q02750 1/20 0.46
MST1R Q04912 1/20 0.46
PTK2 Q05397 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30322863 1.00 MAOA (0.47) MAOAMAOBCYP19A1TNFPLK4
SCHEMBL11559098 0.98 MAOA (0.45) MAOAMAOBCYP19A1TNFPLK4
SCHEMBL11369963 0.89 MAOA (0.50) MAOAMAOBCYP19A1TNFPLK4
SCHEMBL9271489 0.89 SIGMAR1 (0.48) MAOAMAOBCYP19A1TNFPLK4
SCHEMBL30322659 0.89 SIGMAR1 (0.48) MAOAMAOBCYP19A1TNFPLK4
SCHEMBL13741459 0.87 CYP19A1 (0.50) MAOAMAOBCYP19A1KDM4ENPC1
SCHEMBL2239784 0.87 MAOA (0.47) MAOAMAOBCYP19A1TNFPLK4
SCHEMBL30322772 0.87 MAOA (0.47) MAOAMAOBCYP19A1TNFPLK4
SCHEMBL8618246 0.84 SIGMAR1 (0.46) MAOAMAOBCYP19A1TNFKDM4E
Fluorene SCHEMBL28767808 0.82 TNF (0.44) MAOAMAOBCYP19A1TNFPLK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11818949-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-08-09 US disclosed
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2018-07-26 US disclosed
US-9997716-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 US disclosed
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device UDC IRELAND LTD (IE) 2018-05-24 US disclosed
US-9905780-B2 Organic electroluminescent materials containing N-phenylcarboline and organic electroluminescent device by using the same YUAN ZE UNIVERSITY (TW) 2018-02-27 US disclosed
US-20180040836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING CARBOLINE GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME YUAN ZE UNIVERSITY (TW) 2018-02-08 US disclosed
US-9865822-B2 Blue phosphorescence compound and organic light emitting diode using the same LG DISPLAY CO., LTD. (KR) 2018-01-09 US disclosed
US-20180006247-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-01-04 US disclosed
US-20170373260-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays NATIONAL SCIENCE FOUNDATION 2017-12-28 US disclosed
US-5300642-A α, α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-04-05 US disclosed
EP-0311010-B1 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers DU PONT MERCK PHARMA (US) 1994-02-02 EP disclosed
EP-0532054-A1 Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-17 EP disclosed
US-5173489-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1992-12-22 US disclosed
US-5153211-A Enzyme inhibitors ALCON LABORATORIES, INC. (US) 1992-10-06 US disclosed
US-5070100-A COMPLICATIONS OF DIABETES ALCON LABORATORIES, INC. (US) 1991-12-03 US disclosed
US-4864028-A ANTIDIABETIC AGENTS ALCON LABORATORIES, INC. (US) 1989-09-05 US disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 EP disclosed
US-4537892-A ANTIDIABETIC AGENTS ALCON LABORATORIES, INC. (US) 1985-08-27 US disclosed
EP-0137333-A2 Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase ALCON LABORATORIES, INC. (US) 1985-04-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145264-A1 Organic Electroluminescent Device; A Charge Transporting Material For The Organic Electroluminescent Device; And A Luminescent Device, A Display Device And A Lighting System Using The Organic Electroluminescent Device SLC43A1, SLC6A19, AOC3 MAOA 200/4885MAOB 325/4885CYP19A1 1215/4885
US-20180212158-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS MSN, DDT, NECTIN4 MAOA 175/4885MAOB 55/4885CYP19A1 2096/4885
US-11818949-B2 Organic electroluminescent materials and devices EML4, TBCB, TERF2IP MAOA 679/4885MAOB 284/4885CYP19A1 3908/4885
US-20180006247-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TYR, YAP1, PAXBP1 MAOA 2336/4885MAOB 3087/4885CYP19A1 4141/4885
US-20180040836-A1 ORGANIC ELECTROLUMINESCENT MATERIALS CONTAINING CARBOLINE GROUP AND ORGANIC ELECTROLUMINESCENT DEVICE BY USING THE SAME KCNH3, RABL3, CCNL2 MAOA 3086/4885MAOB 2520/4885CYP19A1 3990/4885
US-20180226580-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SLCO4C1, SLCO2A1, SLCO2B1 MAOA 1810/4885MAOB 910/4885CYP19A1 747/4885
US-20170373260-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays DPYD, PAICS, PDCD11 MAOA 1915/4885MAOB 1254/4885CYP19A1 3107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.