SCHEMBL2242452

SCHEMBL2242452

CC(C)C(N)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CCCCN)C(=O)O.[Cu]

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ SLC15A2 Q16348 1/20 0.48
▸ CPB2 Q96IY4 4/20 0.38
▸ ECE1 P42892 1/20 0.37
▸ GHSR Q92847 1/20 0.37
▸ ERAP2 Q6P179 2/20 0.36
▸ ERAP1 Q9NZ08 2/20 0.36
▸ LNPEP Q9UIQ6 2/20 0.36
▸ GNPAT O15228 1/20 0.36
▸ FOLH1 Q04609 1/20 0.36
▸ OPRM1 P35372 1/20 0.35
▸ OPRK1 P41145 1/20 0.35
▸ CPB1 P15086 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2356076 0.99 SLC15A2 (0.48) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL2356070 0.99 SLC15A2 (0.48) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL4588257 0.98 SLC15A2 (0.48) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL2811601 0.92 SLC15A2 (0.49) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL2247594 0.92 SLC15A2 (0.49) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL1959809 0.91 SLC15A2 (0.50) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL5969770 0.91 SLC15A2 (0.50) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL1959812 0.91 SLC15A2 (0.50) SLC15A2CPB2ECE1GHSRERAP2
Hydrochloric Acid SCHEMBL7805623 0.90 SLC15A2 (0.49) SLC15A2CPB2ECE1GHSRERAP2
SCHEMBL4590038 0.90 SLC15A2 (0.49) SLC15A2CPB2ECE1GHSRERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110206790-A1 Antimicrobial Foamable Soaps OHSO CLEAN, INC 2011-08-25 — — US disclosed
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS PROCYTE CORPORATION (US) 2010-09-30 — — US disclosed
EP-1613302-B1 PRESERVED AND STABLE COMPOSITIONS CONTAINING PEPTIDE COPPER COMPLEXES AND METHODS RELATED THERETO PROCYTE CORP (US) 2009-12-23 — — EP disclosed
US-7179789-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2007-02-20 — — US disclosed
US-7128923-B2 Preserved and stable compositions containing peptide copper complexes and method related thereto PROCYTE CORPORATION (US) 2006-10-31 — — US disclosed
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2006-03-09 — — US disclosed
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto PROCYTE CORPORATION (US) 2005-11-24 — — US disclosed
US-20050209130-A1 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-09-22 — — US disclosed
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PROCYTE CORPORATION (US) 2005-09-08 — — US disclosed
US-6927205-B2 Compositions and methods for treatment of psoriasis PROCYTE CORPORATION (US) 2005-08-09 — — US disclosed
US-6927206-B2 Compositions and methods for treatment of rosacea PROCYTE CORPORATION (US) 2005-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209130-A1 Compositions and methods for treatment of rosacea CUTA, AOC1, RCN1 SLC15A2 2091/4885CPB2 2140/4885ECE1 753/4885
US-20060052287-A1 Polyethylene glycol - peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, TFRC SLC15A2 1553/4885CPB2 1673/4885ECE1 862/4885
US-20100249042-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF EYELASHES AND EYEBROWS CUTA, TYR, EYA3 SLC15A2 2514/4885CPB2 1603/4885ECE1 2585/4885
US-20050197282-A1 for topical administration of peptide copper complex with corticosteroids, coal tar, anthralin, calcipotriene, and tazarotene; dermatology; cosmetics PTH1R, TSLP, CYP27B1 SLC15A2 3106/4885CPB2 948/4885ECE1 1039/4885
US-20050260275-A1 Encapsulated peptide copper complexes and compositions and methods related thereto NGLY1, CUTA, CTRC SLC15A2 981/4885CPB2 1007/4885ECE1 1487/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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