Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 8/20 | 0.42 |
| ▸ | PRKACA | P17612 | 4/20 | 0.42 |
| ▸ | PRKX | P51817 | 3/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.42 |
| ▸ | GSK3A | P49840 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.38 |
| ▸ | PRKG1 | Q13976 | 3/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.38 |
| ▸ | PRKCG | P05129 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22441230 | 0.87 | ROCK2 (0.43) | ROCK2ROCK1PRKACAPRKXPRKCQ | |
| SCHEMBL22441232 | 0.87 | ROCK2 (0.43) | ROCK2ROCK1PRKACAPRKXPRKCQ | |
| SCHEMBL29369889 | 0.87 | ROCK2 (0.43) | ROCK2ROCK1PRKACAPRKXPRKCQ | |
| SCHEMBL22457598 | 0.83 | CTSK (0.43) | LPAR3MEN1KMT2A | |
| SCHEMBL22457601 | 0.76 | ROCK1 (0.45) | ROCK2ROCK1CYP3A4AURKALPAR3 | |
| SCHEMBL22458106 | 0.73 | GRM4 (0.51) | CDK5LPAR3LMNAMAPTHTT | |
| SCHEMBL22457756 | 0.73 | PTAFR (0.47) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22441350 | 0.73 | CTSK (0.43) | LPAR3MEN1KMT2A | |
| SCHEMBL22441353 | 0.73 | CTSK (0.43) | LPAR3MEN1KMT2A | |
| SCHEMBL22457745 | 0.72 | TAS1R3 (0.49) | CYP3A4MAPK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2022-01-06 | — | — | US | disclosed |
| US-11040964-B2 | Compounds and methods of use | Ferro Therapeutics, Inc. (US) | 2021-06-22 | — | — | US | disclosed |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | BRIDGEBIO PHARMA, INC. | 2020-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002280-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | ROCK2 804/4885ROCK1 1393/4885PRKACA 1281/4885 |
| US-20200299283-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | ROCK2 804/4885ROCK1 1393/4885PRKACA 1281/4885 |
| US-11040964-B2 | Compounds and methods of use | AIFM2, GPX4, GPX1 | ROCK2 804/4885ROCK1 1393/4885PRKACA 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.