Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 10/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247341 | 0.86 | C3AR1 (0.53) | C3AR1SUCNR1 | |
| SCHEMBL2247800 | 0.85 | HPGDS (0.52) | C3AR1HPGDSMMP12SUCNR1MMP2 | |
| SCHEMBL3578207 | 0.84 | MMP2 (0.46) | MMP2 | |
| SCHEMBL2247526 | 0.80 | MMP12 (0.58) | HPGDSMMP12MMP2MMP8PTPN1 | |
| SCHEMBL2243866 | 0.80 | C3AR1 (0.67) | C3AR1HPGDSMMP12SUCNR1 | |
| SCHEMBL2244822 | 0.80 | KDM4E (0.50) | C3AR1HPGDSMMP12MMP2MMP8 | |
| SCHEMBL2245137 | 0.78 | C3AR1 (0.53) | C3AR1HPGDSMMP12SUCNR1MMP2 | |
| SCHEMBL2248650 | 0.78 | LMNA (0.56) | HPGDSMMP12MMP2MMP8PTPN1 | |
| SCHEMBL10571826 | 0.73 | NAALAD2 (0.57) | — | |
| SCHEMBL1605515 | 0.73 | NAALAD2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998965-B2 | Glutamate aggrecanase inhibitors | WYETH LLC (US) | 2011-08-16 | — | — | US | disclosed |