SCHEMBL22485386

SCHEMBL22485386

NCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CCCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CCKBR P32239 3/20 0.55
▸ MMP2 P08253 6/20 0.53
▸ MMP9 P14780 6/20 0.53
▸ MMP8 P22894 6/20 0.53
▸ MMP14 P50281 6/20 0.53
▸ GHSR Q92847 4/20 0.52
▸ MMP11 P24347 1/20 0.52
▸ KISS1R Q969F8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22339065 0.93 CCKBR (0.63) CCKBRMMP2MMP9MMP8MMP14
SCHEMBL14811912 0.90 MC4R (0.57) CCKBRKISS1R
SCHEMBL22330610 0.87 GRPR (0.54) CCKBRMMP2MMP9MMP8MMP14
SCHEMBL30294163 0.87 GRPR (0.54) CCKBRMMP2MMP9MMP8MMP14
SCHEMBL20045524 0.87 GRPR (0.54) CCKBRMMP2MMP9MMP8MMP14
SCHEMBL22339063 0.86 MC4R (0.53) CCKBRKISS1R
SCHEMBL22339064 0.85 MC4R (0.55) CCKBRKISS1R
SCHEMBL29489105 0.84 KISS1R (0.56) CCKBRGHSRKISS1R
SCHEMBL5501891 0.84 KISS1R (0.55) KISS1R
SCHEMBL22485392 0.83 MC4R (0.54) CCKBRKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3704134-B1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS BV (NL) 2021-12-22 — — EP disclosed
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES DSM IP ASSETS B.V. (NL) 2020-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308222-A1 ANTIMICROBIAL TETRAPEPTIDES VIP, CLPP, SGTA CCKBR 2568/4885MMP2 2589/4885MMP9 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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