Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 6/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21224111 | 0.82 | PDK1 (0.47) | SLC34A1HPGDPDK1PDK2 | |
| SCHEMBL5023330 | 0.76 | SLC34A1 (0.49) | SLC34A1ELANEKDM4EALDH1A1HPGD | |
| SCHEMBL26659330 | 0.75 | ALDH1A1 (0.45) | SLC34A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL5023848 | 0.74 | GABRA2 (0.48) | SLC34A1ELANEKDM4EALDH1A1HPGD | |
| SCHEMBL2997892 | 0.73 | CA12 (0.56) | ELANEKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14152735 | 0.73 | ALDH1A1 (0.55) | SLC34A1ELANEKDM4EALDH1A1HPGD | |
| SCHEMBL5937205 | 0.72 | ELANE (0.44) | SLC34A1ELANEKDM4EALDH1A1HPGD | |
| SCHEMBL25328209 | 0.72 | KDM4E (0.56) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL8310828 | 0.72 | KDM4E (0.58) | SLC34A1KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28306812 | 0.71 | CA12 (0.61) | ELANEKDM4EALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070910-A1 | NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2026-03-12 | — | — | US | disclosed |
| US-20240300952-A1 | NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2024-09-12 | — | — | US | disclosed |
| CN-111655692-B | Nitrogen-containing heterocyclic amide compound and medical application thereof | 日本烟草产业株式会社 | 2023-10-10 | — | — | CN | disclosed |
| US-20210284644-A1 | NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2021-09-16 | — | — | US | disclosed |
| US-20210284644-A1 | NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC (JP) | 2021-09-16 | — | — | US | disclosed |
| EP-3747888-A1 | NITROGENATED HETEROCYCLIC AMIDE COMPOUND, AND USE THEREOF FOR MEDICAL PURPOSES | Japan Tobacco Inc. (JP) | 2020-12-09 | — | — | EP | disclosed |
| US-10800784-B2 | Nitrogen-containing heterocyclic amide compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2020-10-13 | — | — | US | disclosed |
| US-10800784-B2 | Nitrogen-containing heterocyclic amide compound and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2020-10-13 | — | — | US | disclosed |
| CN-111655692-A | Nitrogen-containing heterocyclic amide compound and medical application thereof | 日本烟草产业株式会社 | 2020-09-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800784-B2 | Nitrogen-containing heterocyclic amide compound and pharmaceutical use thereof | IDH2, PC, FH | SLC34A1 1469/4885ELANE 1926/4885KDM4E 4589/4885 |
| US-20240300952-A1 | NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF | IDH2, PC, FH | SLC34A1 1469/4885ELANE 1926/4885KDM4E 4589/4885 |
| US-20210284644-A1 | NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF | IDH2, PC, FH | SLC34A1 1469/4885ELANE 1926/4885KDM4E 4589/4885 |
| US-20260070910-A1 | NITROGEN-CONTAINING HETEROCYCLIC AMIDE COMPOUND AND PHARMACEUTICAL USE THEREOF | PC, CS, IDH2 | SLC34A1 1699/4885ELANE 1423/4885KDM4E 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.