Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22545448 | 0.84 | TSHR (0.41) | RAB9AALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL22545267 | 0.83 | NPSR1 (0.45) | ALDH1A1CA2MAPTNPSR1CA1 | |
| SCHEMBL22527632 | 0.83 | PTPRC (0.36) | CA2L3MBTL1CA1 | |
| SCHEMBL22545577 | 0.81 | HDAC8 (0.41) | RAB9AALDH1A1TSHRKAT6A | |
| SCHEMBL25678174 | 0.79 | CACNA1F (0.41) | RAB9AALDH1A1CA2MAPTMEN1 | |
| SCHEMBL22545513 | 0.77 | CA2 (0.35) | RAB9AALDH1A1TSHRKAT6ACA2 | |
| SCHEMBL22545460 | 0.77 | AAK1 (0.32) | — | |
| SCHEMBL16642002 | 0.66 | PSIP1 (0.50) | ALDH1A1TSHRCA2HSD11B1 | |
| SCHEMBL22181477 | 0.66 | ALDH1A1 (0.46) | ALDH1A1CA2 | |
| SCHEMBL28584804 | 0.66 | TSHR (0.52) | ALDH1A1TSHRCA2TDP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331745-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2023-10-19 | — | — | US | disclosed |
| EP-3707145-B1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK AS (DK) | 2023-06-21 | — | — | EP | disclosed |
| US-11186595-B2 | Glucose-sensitive albumin-binding derivatives | NOVO NORDISK A/S (DK) | 2021-11-30 | — | — | US | disclosed |
| US-20200325160-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | NOVO NORDISK A/S (DK) | 2020-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331745-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, DBI, FABP4 | RAB9A 2780/4885ALDH1A1 1240/4885TSHR 3575/4885 |
| US-11186595-B2 | Glucose-sensitive albumin-binding derivatives | ALB, GPR119, MLX | RAB9A 1733/4885ALDH1A1 456/4885TSHR 1295/4885 |
| US-20200325160-A1 | GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES | ALB, GPR119, MLX | RAB9A 1733/4885ALDH1A1 456/4885TSHR 1295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.