SCHEMBL22557572

SCHEMBL22557572

Nc1cc(S(=O)(=O)c2ccccc2)cc(Cl)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.48
GAA P10253 6/20 0.46
MAPT P10636 1/20 0.46
ALDH1A1 P00352 5/20 0.43
ALOX15 P16050 3/20 0.43
HSD17B10 Q99714 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
PKM P14618 3/20 0.43
HTT P42858 2/20 0.43
HPGD P15428 2/20 0.43
POLB P06746 1/20 0.41
GFER P55789 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2811005 0.89 GAA (0.50) HTR6GAAMAPTALDH1A1ALOX15
SCHEMBL11112123 0.79 CA12 (0.61) HTR6GAAMAPTALDH1A1ALOX15
SCHEMBL4615892 0.79 HTR6 (0.52) HTR6GAAMAPTALDH1A1MEN1
SCHEMBL1347471 0.77 HSD17B10 (0.50) GAAMAPTALDH1A1ALOX15HSD17B10
SCHEMBL8459698 0.77 HSD17B10 (0.50) GAAMAPTALDH1A1ALOX15HSD17B10
SCHEMBL22556884 0.76 KIF18A (0.54) GAAMAPTALDH1A1MEN1KMT2A
SCHEMBL9463563 0.76 CA1 (0.63) GAAMAPTMEN1KMT2APKM
SCHEMBL6935562 0.76 CASP6 (0.53) GAAMAPTALDH1A1ALOX15HSD17B10
SCHEMBL9805864 0.75 HTR6 (0.52) HTR6GAAMAPTALDH1A1POLB
SCHEMBL565124 0.75 GAA (0.81) HTR6GAAMAPTALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384769-B2 Heteroaryl-substituted aminoalkyl azole compounds as pesticides ELANCO ANIMAL HEALTH GMBH (DE) 2025-08-12 US disclosed
CN-113939509-B Novel heteroaryl substituted aminoalkylazole compounds as pesticides 拜耳动物保健有限责任公司 2024-11-29 CN disclosed
US-20230046680-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES ELANCO ANIMAL HEALTH GMBH (DE) 2023-02-16 US disclosed
US-20230046680-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES ELANCO ANIMAL HEALTH GMBH (DE) 2023-02-16 US disclosed
EP-3956325-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES Bayer Animal Health GmbH (DE) 2022-02-23 EP disclosed
CN-113939509-A Novel heteroaryl substituted aminoalkylazole compounds as pesticides 拜耳动物保健有限责任公司 2022-01-14 CN disclosed
WO-2020212235-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2020-10-22 WO disclosed
WO-2020212235-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES BAYER ANIMAL HEALTH GMBH (DE) 2020-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230046680-A1 NOVEL HETEROARYL-SUBSTITUTED AMINOALKYL AZOLE COMPOUNDS AS PESTICIDES DDT, CRY1, CYP4F3 HTR6 4646/4885GAA 3621/4885MAPT 4067/4885
US-12384769-B2 Heteroaryl-substituted aminoalkyl azole compounds as pesticides DDT, CRY1, AAAS HTR6 4500/4885GAA 3657/4885MAPT 4242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.