SCHEMBL9463563

SCHEMBL9463563

Nc1cc(S(N)(=O)=O)cc(Cl)c1O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 13/20 0.63
CA2 P00918 13/20 0.63
CA9 Q16790 12/20 0.63
CA12 O43570 7/20 0.57
CA4 P22748 3/20 0.57
CA6 P23280 3/20 0.57
CA5A P35218 3/20 0.57
CA7 P43166 3/20 0.57
CA14 Q9ULX7 3/20 0.57
CA5B Q9Y2D0 3/20 0.57
APEX1 P27695 2/20 0.57
POLB P06746 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
LMNA P02545 1/20 0.52
CYP2C9 P11712 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5564627 0.89 CA1 (0.64) CA1CA2CA9CA12CA4
SCHEMBL2811005 0.85 GAA (0.50) CA1CA2CA9CA12CA4
SCHEMBL6935562 0.83 CASP6 (0.53) CA1CA2CA9CA12CA4
SCHEMBL6906930 0.82 CA1 (0.69) CA1CA2CA9CA12CA4
SCHEMBL29780561 0.80 CA2 (0.65) CA1CA2CA9CA12CA4
SCHEMBL3781532 0.78 CA1 (1.00) CA1CA2CA9CA12CA4
SCHEMBL11060267 0.77 ALDH1A1 (0.50) CA1CA2CA9CA12CA4
SCHEMBL21487375 0.77 CA2 (0.61) CA1CA2CA9CA12CA4
SCHEMBL22557572 0.76 HTR6 (0.48) CA1CA2CA9CA12CA4
SCHEMBL7993257 0.75 CA2 (0.75) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5215925-A Complexing with formazan dyes at a PH from about 8.5 to 10.5 and colorimetric analysis EASTMAN KODAK COMPANY (US) 1993-06-01 US disclosed
EP-0244196-B1 HYDROXY-SUBSTITUTED CYANOFORMAZANS AND THEIR USE IN ANALYTICAL COMPOSITIONS AND METHODS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-01-29 EP disclosed
EP-0244196-A1 Hydroxy-substituted cyanoformazans and their use in analytical compositions and methods EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1987-11-04 EP disclosed
US-4524123-A POLYETHERSILOXANE COPOLYMERS, HIGH MOLECULAR WEIGHT POLYETHYLEN, AND EMULSIFIER AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1985-06-18 US disclosed
EP-0054230-B1 MONOAZO DYESTUFFS AND USE AS IMAGE-FORMING DYESTUFFS IN COLOUR-PHOTOGRAPHIC REGISTRATION MATERIALS Agfa-Gevaert AG (DE) 1985-03-20 EP disclosed
US-4418143-A Color photographic recording material AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
US-4396710-A Photographic recording material with metal complexable, heterocyclic azo dye AFGA-GEVAERT AKTIENGESELLSCHAFT (DE) 1983-08-02 US disclosed
EP-0054230-A2 Monoazo dyestuffs and use as image-forming dyestuffs in colour-photographic registration materials Agfa-Gevaert AG (DE) 1982-06-23 EP disclosed
US-4141890-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed