SCHEMBL2256279

SCHEMBL2256279

COCCOC(=O)CC(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP3 P08254 1/20 0.41
MMP9 P14780 1/20 0.41
MMP13 P45452 1/20 0.41
TSHR P16473 2/20 0.39
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
CYP3A4 P08684 1/20 0.37
ALOX15 P16050 1/20 0.37
PRKCA P17252 2/20 0.37
CA2 P00918 1/20 0.36
MET P08581 1/20 0.35
DPP4 P27487 1/20 0.35
DGKA P23743 1/20 0.34
PRKD3 O94806 1/20 0.33
PRKCG P05129 1/20 0.33
PRKCB P05771 1/20 0.33
PRKCH P24723 1/20 0.33
PRKCI P41743 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19514131 0.94 MMP1 (0.37) MMP1MMP2MMP3MMP9MMP13
SCHEMBL18378814 0.91 MMP1 (0.46) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9935621 0.87 MMP1 (0.38) MMP1MMP2MMP3MMP9MMP13
SCHEMBL7631813 0.84 MMP1 (0.42) MMP1MMP2MMP3MMP9MMP13
SCHEMBL7630194 0.84 MMP1 (0.42) MMP1MMP2MMP3MMP9MMP13
SCHEMBL15383208 0.83 TSHR (0.37) TSHRALDH1A1TDP1CYP3A4ALOX15
SCHEMBL22115803 0.83 TSHR (0.37) MMP1MMP2MMP3MMP9MMP13
SCHEMBL881376 0.81 MMP1 (0.43) MMP1MMP2MMP3MMP9MMP13
SCHEMBL22115798 0.81 ALDH1A1 (0.38) MMP1MMP2MMP3TSHRALDH1A1
SCHEMBL18356850 0.81 TSHR (0.36) TSHRALDH1A1TDP1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025922-A1 TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS MERCK HEALTHCARE KGAA (DE) 2024-01-25 US disclosed
US-20230276792-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND CLOQUINTOCET-MEXYL BAYER AKTIENGESELLSCHAFT (DE) 2023-09-07 US disclosed
US-20230217926-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND ISOXADIFEN-ETHYL BAYER AKTIENGESELLSCHAFT (DE) 2023-07-13 US disclosed
US-20230200393-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND METCAMIFEN BAYER AKTIENGESELLSCHAFT (DE) 2023-06-29 US disclosed
US-20230200390-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND MEFENPYR-DIETHYL BAYER AKTIENGESELLSCHAFT (DE) 2023-06-29 US disclosed
US-20230200394-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND BENOXACOR BAYER AKTIENGESELLSCHAFT (DE) 2023-06-29 US disclosed
US-20230189808-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND FURILAZOLE BAYER AKTIENGESELLSCHAFT (DE) 2023-06-22 US disclosed
CN-111349185-B Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔能源有限公司 2023-02-03 CN disclosed
US-11427657-B2 Solid catalyst for propylene polymerization and method of producing block copolymer using the same HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2022-08-30 US disclosed
CN-111349185-A Solid catalyst for propylene polymerization and method for producing block copolymer using the same 韩华道达尔有限公司 2020-06-30 CN disclosed
US-20130225398-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product DOW GLOBAL TECHNOLOGIES LLC (US) 2013-08-29 US disclosed
WO-2012087531-A1 CATALYST COMPOSITION WITH ALKOXYALKYL ESTER INTERNAL ELECTRON DONOR AND POLYMER FROM SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 WO disclosed
US-20120157642-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W.R. GRACE & CO.-CONN. 2012-06-21 US disclosed
US-20120157295-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product W. R. GRACE & CO. - CONN. 2012-06-21 US disclosed
US-20120157642-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W.R. GRACE & CO.-CONN. 2012-06-21 US disclosed
US-20120157642-A1 Catalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Polymer from Same W.R. GRACE & CO.-CONN. 2012-06-21 US disclosed
US-20120157295-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product W. R. GRACE & CO. - CONN. 2012-06-21 US disclosed
US-20120157295-A1 Process for Producing Procatalyst Composition with Alkoxyalkyl Ester Internal Electron Donor and Product W. R. GRACE & CO. - CONN. 2012-06-21 US disclosed
US-20110195846-A1 Liquid Pyraclostrobin-Containing Crop Protection Formulations BASF SE (DE) 2011-08-11 US disclosed
US-20110195839-A1 Liquid Aqueous Crop Protection Formulations BASF SE (DE) 2011-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230200394-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND BENOXACOR AADAC, CBR3, BROX MMP1 2092/4885MMP2 1886/4885MMP3 2387/4885
US-20230276792-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND CLOQUINTOCET-MEXYL AADAC, ABAT, ABCG2 MMP1 3507/4885MMP2 3284/4885MMP3 3521/4885
US-20110195839-A1 Liquid Aqueous Crop Protection Formulations AQP1, GANC, BROX MMP1 885/4885MMP2 1776/4885MMP3 1466/4885
US-20230217926-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND ISOXADIFEN-ETHYL AADAC, CYP4F12, IDH2 MMP1 2609/4885MMP2 2183/4885MMP3 3297/4885
US-20230200393-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND METCAMIFEN MET, MTX2, AADAC MMP1 1096/4885MMP2 750/4885MMP3 1274/4885
US-20240025922-A1 TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS PDXK, DTYMK, HIPK1 MMP1 4063/4885MMP2 3359/4885MMP3 2930/4885
US-20230200390-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND MEFENPYR-DIETHYL DDT, AADAC, EFHD2 MMP1 2315/4885MMP2 2116/4885MMP3 2636/4885
US-20230189808-A1 SELECTIVE HERBICIDES BASED ON SUBSTITUTED ISOXAZOLIN CARBOXAMIDES AND FURILAZOLE AADAC, NOTUM, CYP4X1 MMP1 1589/4885MMP2 2009/4885MMP3 2639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.