Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2934 | 0.89 | GPR119 (0.43) | NR1H4OXTRAVPR1AGPR119ALDH1A1 | |
| SCHEMBL3058 | 0.81 | OXTR (0.41) | NR1H4OXTRAVPR1AGPR119ALDH1A1 | |
| SCHEMBL2776 | 0.80 | LTB4R2 (0.55) | NR1H4OXTRAVPR1AL3MBTL1ATM | |
| SCHEMBL7276526 | 0.80 | GPR119 (0.42) | NR1H4OXTRAVPR1AGPR119ALDH1A1 | |
| SCHEMBL2260 | 0.80 | ATM (0.42) | NR1H4OXTRAVPR1AALDH1A1SMN1; SMN2 | |
| SCHEMBL7280581 | 0.79 | OXTR (0.44) | NR1H4OXTRAVPR1AGPR119ESR2 | |
| SCHEMBL7278162 | 0.76 | OXTR (0.40) | NR1H4OXTRAVPR1AGPR119ALDH1A1 | |
| SCHEMBL2104 | 0.73 | NLRP3 (0.43) | OXTRAVPR1AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3536 | 0.72 | MEN1 (0.44) | OXTRAVPR1AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3537 | 0.72 | MEN1 (0.44) | OXTRAVPR1AALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |