Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278162 | 0.84 | OXTR (0.40) | OXTRAVPR1ANR1H4GPR119ALDH1A1 | |
| SCHEMBL2934 | 0.82 | GPR119 (0.43) | OXTRAVPR1ANR1H4GPR119ALDH1A1 | |
| SCHEMBL2261 | 0.81 | NR1H4 (0.41) | OXTRAVPR1ANR1H4GPR119ALDH1A1 | |
| SCHEMBL2307 | 0.80 | LTB4R2 (0.54) | OXTRAVPR1ANR1H4FFAR1AKR1B1 | |
| SCHEMBL2306 | 0.80 | LTB4R2 (0.54) | OXTRAVPR1ANR1H4FFAR1AKR1B1 | |
| SCHEMBL3057 | 0.77 | CTSB (0.43) | OXTRAVPR1AFFAR1AKR1B1SRC | |
| SCHEMBL3059 | 0.77 | CTSB (0.43) | OXTRAVPR1AFFAR1AKR1B1SRC | |
| SCHEMBL7276526 | 0.77 | GPR119 (0.42) | OXTRAVPR1ANR1H4GPR119ALDH1A1 | |
| SCHEMBL2104 | 0.73 | NLRP3 (0.43) | OXTRAVPR1AALDH1A1GAAL3MBTL1 | |
| SCHEMBL2604 | 0.70 | NLRP3 (0.41) | OXTRAVPR1ANR1H4ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |