Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.34 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650346 | 0.86 | ROCK2 (0.37) | ROCK2LIPEGPR119KDM4DMMP1 | |
| SCHEMBL22650383 | 0.85 | FPR2 (0.35) | ROCK2LIPEHRH3FPR1FPR2 | |
| SCHEMBL22650408 | 0.84 | PDK2 (0.36) | ROCK2GPR119KDM4DUSP30 | |
| SCHEMBL23975899 | 0.82 | RIPK1 (0.42) | — | |
| SCHEMBL22650413 | 0.78 | DDB1 (0.38) | ROCK2HDAC8HDAC6FPR1FPR2 | |
| SCHEMBL5958870 | 0.78 | HDAC8 (0.37) | HDAC8HDAC6FPR1FPR2F10 | |
| SCHEMBL30599761 | 0.76 | KDM4D (0.38) | GPR119KDM4D | |
| SCHEMBL29418458 | 0.76 | KDM4D (0.38) | GPR119KDM4D | |
| SCHEMBL594199 | 0.76 | GPR119 (0.46) | GPR119KDM4DUSP30HSD11B1CASP6 | |
| SCHEMBL14022306 | 0.75 | FPR2 (0.45) | FPR1FPR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |