Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.40 |
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CDK4 | P11802 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CCND1 | P24385 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 8/20 | 0.38 |
| ▸ | BRD4 | O60885 | 5/20 | 0.38 |
| ▸ | IKBKB | O14920 | 3/20 | 0.38 |
| ▸ | CHUK | O15111 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650502 | 0.89 | CDK4 (0.43) | CDK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL22650549 | 0.88 | ZAP70 (0.42) | CDK2CDK1CCNB1CDK9IKBKB | |
| SCHEMBL22650496 | 0.87 | EGFR (0.38) | CDK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL22650464 | 0.77 | CDK6 (0.44) | CDK2CDK4CCND1CDK9CCNT1 | |
| SCHEMBL22650579 | 0.75 | CDK4 (0.48) | CDK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL22650426 | 0.74 | IKBKB (0.42) | CDK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL22650775 | 0.73 | CDK4 (0.44) | CDK2CDK1CDK4CDK9CCNA2 | |
| SCHEMBL22650515 | 0.72 | SYK (0.35) | CDK2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL22650503 | 0.68 | MAPK14 (0.46) | CDK2CDK1CCNB1CCNE1CDK9 | |
| SCHEMBL22650407 | 0.68 | L3MBTL1 (0.37) | CDK2CDK1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |