Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZAP70 | P43403 | 11/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 2/20 | 0.42 |
| ▸ | PRKCH | P24723 | 2/20 | 0.42 |
| ▸ | PRKCI | P41743 | 2/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.42 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.42 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650501 | 0.88 | CDK2 (0.40) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL22650496 | 0.83 | EGFR (0.38) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL22650502 | 0.78 | CDK4 (0.43) | CCNA2CDK2CDK1CCNB1CCNT1 | |
| SCHEMBL22650579 | 0.75 | CDK4 (0.48) | CCNA2CDK2CDK1CCNB1CCNA1 | |
| SCHEMBL22650775 | 0.74 | CDK4 (0.44) | CCNA2CDK2CDK1CDK9 | |
| SCHEMBL22650464 | 0.74 | CDK6 (0.44) | EGFRCCNA2CDK2CCNT1CDK9 | |
| SCHEMBL22650515 | 0.73 | SYK (0.35) | ZAP70PRKCBEGFRCDK2CDK1 | |
| SCHEMBL22650430 | 0.73 | MYLK4 (0.43) | ZAP70PRKD3PRKCGPRKCBLCK | |
| SCHEMBL22650503 | 0.70 | MAPK14 (0.46) | CCNA2CDK2CDK1CCNB1CCNA1 | |
| SCHEMBL22650407 | 0.70 | L3MBTL1 (0.37) | CCNA2CDK2CDK1CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |