Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.34 |
| ▸ | LGMN | Q99538 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22650571 | 0.81 | CCR5 (0.39) | CCR5GPR119LIPE | |
| SCHEMBL31347314 | 0.77 | BPTF (0.41) | BPTFTSHRDPP4 | |
| SCHEMBL22650563 | 0.77 | BPTF (0.41) | BPTFTSHRDPP4 | |
| SCHEMBL22650570 | 0.77 | LIPE (0.37) | CCR5GPR119LIPE | |
| SCHEMBL4259518 | 0.73 | PDE10A (0.43) | GPR119MCHR1LGMN | |
| SCHEMBL27760852 | 0.73 | PDE10A (0.43) | GPR119MCHR1LGMN | |
| SCHEMBL4339043 | 0.73 | CCR5 (0.45) | CCR5GPR119LGMN | |
| SCHEMBL22650573 | 0.73 | LIPE (0.35) | GPR119MCHR1DPP4LIPE | |
| SCHEMBL22650383 | 0.72 | FPR2 (0.35) | TSHRMCHR1LIPEHDAC1 | |
| SCHEMBL4349234 | 0.72 | CCR5 (0.44) | CCR5GPR119MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |