Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.35 |
| ▸ | FPR1 | P21462 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 2/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23975899 | 0.85 | RIPK1 (0.42) | HTR2CSLC6A4HTR2ARIPK1TSHR | |
| SCHEMBL22650381 | 0.85 | ROCK2 (0.38) | FPR2FPR1LIPEF10HSD11B1 | |
| SCHEMBL22650346 | 0.80 | ROCK2 (0.37) | HTR2CSLC6A4HTR2ALIPEROCK2 | |
| SCHEMBL22650382 | 0.78 | FPR2 (0.43) | FPR2FPR1F10 | |
| SCHEMBL4259518 | 0.77 | PDE10A (0.43) | FPR2FPR1HSD11B1KDM4DMCHR1 | |
| SCHEMBL27760852 | 0.77 | PDE10A (0.43) | FPR2FPR1HSD11B1KDM4DMCHR1 | |
| SCHEMBL22650408 | 0.74 | PDK2 (0.36) | HTR2CSLC6A4HTR2AROCK2KDM4D | |
| SCHEMBL3000521 | 0.72 | HSD11B1 (0.37) | FPR2FPR1HTR2CSLC6A4F10 | |
| SCHEMBL22650572 | 0.72 | CCR5 (0.38) | LIPEHDAC1TSHRMCHR1 | |
| SCHEMBL29418458 | 0.71 | KDM4D (0.38) | KDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020224568-A1 | CDK INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2020-11-12 | — | — | WO | disclosed |