SCHEMBL2267110

SCHEMBL2267110

CCC[SiH](NCC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 1/20 0.33
TP53 P04637 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SIGMAR1 Q99720 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268688 0.88 SIGMAR1 (0.34) KCNN4ALDH1A1SIGMAR1GAAHPGD
SCHEMBL2102165 0.85 GAA (0.31) GAA
SCHEMBL2269967 0.83 KCNN4 (0.35) KCNN4TP53SIGMAR1
SCHEMBL2103965 0.81 TAAR1 (0.38) ALDH1A1SIGMAR1KDM4E
SCHEMBL2267562 0.81 LMNA (0.33) KCNN4TP53KDM4E
SCHEMBL2100481 0.80 CACNA2D1 (0.36) ALDH1A1SIGMAR1
SCHEMBL2270813 0.76 ALDH1A1 (0.34) KCNN4ALDH1A1
SCHEMBL2101841 0.74 SIGMAR1 (0.34) SIGMAR1
SCHEMBL2268660 0.73 KCNN4 (0.38) KCNN4TP53ALDH1A1SIGMAR1KDM4E
SCHEMBL2102932 0.73 KCNN4 (0.38) KCNN4TP53ALDH1A1SIGMAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed