Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255463 | 0.79 | ALDH1A1 (0.43) | TDP1MAPTALDH1A1POLBHSD17B10 | |
| SCHEMBL28919595 | 0.77 | LMNA (0.60) | TDP1MAPTALDH1A1POLBHSD17B10 | |
| SCHEMBL11884322 | 0.75 | FAAH (0.47) | MAPTPOLBHSD17B10 | |
| SCHEMBL11883175 | 0.72 | MAPT (0.41) | TDP1MAPTALDH1A1POLBHSD17B10 | |
| Hydrochloric Acid SCHEMBL21829144 | 0.72 | NAAA (0.40) | POLBTSHRKDM4EHPGDGAA | |
| SCHEMBL3366538 | 0.70 | — | — | |
| SCHEMBL11287692 | 0.70 | TDP1 (0.56) | TDP1ALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL11597856 | 0.70 | TDP1 (0.56) | TDP1ALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL17453246 | 0.70 | TSHR (0.50) | TDP1MAPTALDH1A1TSHRKDM4E | |
| SCHEMBL14972375 | 0.70 | NAAA (0.50) | TDP1MAPTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358941-B2 | — | — | 2022-06-14 | — | — | US | disclosed |
| US-20200361879-A1 | COMPOUNDS HAVING A STABILIZING EFFECT, METHOD FOR PRODUCING SAID COMPOUNDS, COMPOSITION CONTAINING SAID STABILIZING COMPOUNDS, METHOD FOR STABILIZING AN ORGANIC COMPONENT, AND USE OF STABILIZING COMPOUNDS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) | 2020-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358941-B2 | — | OGG1, SOD1, ERCC5 | TDP1 319/4885MAPT 117/4885ALDH1A1 250/4885 |
| US-20200361879-A1 | COMPOUNDS HAVING A STABILIZING EFFECT, METHOD FOR PRODUCING SAID COMPOUNDS, COMPOSITION CONTAINING SAID STABILIZING COMPOUNDS, METHOD FOR STABILIZING AN ORGANIC COMPONENT, AND USE OF STABILIZING COMPOUNDS | OGG1, SOD1, AOX1 | TDP1 962/4885MAPT 156/4885ALDH1A1 323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.