Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5577325 | 0.71 | MGLL (0.43) | GSK3AGSK3BMGLLALDH1A1BLM | |
| SCHEMBL208215 | 0.65 | ALDH1A1 (0.38) | GSK3AGSK3BMGLLALDH1A1BLM | |
| SCHEMBL16256331 | 0.63 | — | — | |
| SCHEMBL2756782 | 0.62 | ALDH1A1 (0.64) | GSK3AGSK3BMGLLALDH1A1BLM | |
| SCHEMBL9311835 | 0.61 | ALDH1A1 (0.56) | GSK3AGSK3BMGLLALDH1A1BLM | |
| SCHEMBL709406 | 0.61 | MGLL (0.42) | GSK3AGSK3BMGLLALDH1A1BLM | |
| SCHEMBL720720 | 0.61 | MGLL (0.43) | GSK3AGSK3BMGLLALDH1A1BLM | |
| SCHEMBL11571457 | 0.60 | MGLL (0.32) | GSK3AGSK3BMGLL | |
| SCHEMBL8097898 | 0.60 | GAA (0.34) | GSK3AGSK3BMGLLALDH1A1BLM | |
| SCHEMBL976025 | 0.59 | MGLL (0.72) | GSK3AGSK3BMGLLALDH1A1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003078-B2 | Targeted MR imaging agents | BARNES-JEWISH HOSPITAL (US) | 2011-08-23 | — | — | US | disclosed |
| US-20080247943-A1 | Blood Clot-Targeted Nanoparticles | KEREOS, INC. | 2008-10-09 | — | — | US | disclosed |
| EP-1539252-A4 | BLOOD CLOT-TARGETED NANOPARTICLES | BARNES JEWISH HOSPITAL (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007115115-A2 | TARGETED MR IMAGING AGENTS | KEREOS, INC. (US) | 2007-10-11 | — | — | WO | disclosed |
| US-20070237721-A1 | TARGETED MR IMAGING AGENTS | KEREOS, INC. | 2007-10-11 | — | — | US | disclosed |
| EP-1539252-A2 | BLOOD CLOT-TARGETED NANOPARTICLES | Barnes-Jewish Hospital (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017907-A2 | BLOOD CLOT-TARGETED NANOPARTICLES | BARNES-JEWISH HOSPITAL (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080247943-A1 | Blood Clot-Targeted Nanoparticles | FGB, PLAT, PLG | GSK3A 4643/4885GSK3B 4578/4885MGLL 164/4885 |
| US-20070237721-A1 | TARGETED MR IMAGING AGENTS | TSPO, ARNT, RXFP4 | GSK3A 4222/4885GSK3B 4220/4885MGLL 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.