SCHEMBL2267927

SCHEMBL2267927

CC[SiH](NC)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
CYP2D6 P10635 1/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
TAAR1 Q96RJ0 4/20 0.33
ATM Q13315 1/20 0.33
KCNN4 O15554 2/20 0.32
CALM1 P0DP23 1/20 0.32
IDO1 P14902 1/20 0.31
SLC18A2 Q05940 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRA1A P35348 1/20 0.30
HTR1D P28221 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2267562 0.82 LMNA (0.33) LMNACYP2D6TP53TSHRKDM4E
SCHEMBL2269967 0.79 KCNN4 (0.35) LMNACYP2D6TP53KCNN4IDO1
SCHEMBL27967013 0.79 LMNA (0.34) LMNACYP2D6TSHRKDM4ECYP3A4
SCHEMBL2268690 0.79 SIGMAR1 (0.35) TP53TSHRMAPTSIGMAR1
SCHEMBL2102345 0.73 GAA (0.33) KCNN4
SCHEMBL2102330 0.71 CACNA2D1 (0.35) KDM4EMAPTIDO1SIGMAR1CHRM2
SCHEMBL416585 0.69 TP53 (0.41) LMNATP53TSHRATMKCNN4
SCHEMBL2101602 0.69 TSHR (0.41) LMNACYP2D6TSHRKDM4ECYP3A4
SCHEMBL8381981 0.69 TP53 (0.41) LMNATP53TSHRKDM4EATM
SCHEMBL2268375 0.69 TSHR (0.41) LMNACYP2D6TSHRKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed