SCHEMBL2270959

SCHEMBL2270959

O=C(Nc1cc(CCc2ccccc2)ccc1C(=O)O)c1ccc2occc2c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 4/20 0.47
WNT3A P56704 4/20 0.47
NAMPT P43490 1/20 0.47
MAPT P10636 3/20 0.45
IDO1 P14902 1/20 0.45
LMNA P02545 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA4 P22748 2/20 0.44
CA7 P43166 2/20 0.44
PLK1 P53350 6/20 0.44
PLK3 Q9H4B4 4/20 0.44
DHODH Q02127 1/20 0.44
FOXO1 Q12778 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2276797 0.91 LTC4S (0.49) CTNNB1WNT3AMAPTPLK1PLK3
SCHEMBL2272399 0.84 ACLY (0.59) CTNNB1WNT3ANAMPTMAPTIDO1
SCHEMBL4217800 0.82 MEN1 (0.49) CTNNB1WNT3AMAPTIDO1
SCHEMBL2271421 0.81 DHODH (0.63) MAPTPLK1PLK3DHODH
SCHEMBL2275929 0.81 KMT2A (0.62) MAPTCA12CA1CA4CA7
SCHEMBL2269797 0.80 SERPINE1 (0.50) NAMPTDHODH
SCHEMBL2272111 0.79 SUCNR1 (0.59) MAPTDHODH
SCHEMBL2277740 0.79 CYP1A2 (0.58)
SCHEMBL2270925 0.79 PLK1 (0.57) MAPTCA12CA1CA4CA7
SCHEMBL2270906 0.78 MEN1 (0.56) MAPTLMNACA12CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 CTNNB1 1347/4885WNT3A 667/4885NAMPT 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.