Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | ACLY | P53396 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KCNK2 | O95069 | 3/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2272852 | 0.89 | CASP3 (0.57) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL2272541 | 0.88 | PTGS2 (0.63) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL2274795 | 0.87 | NPC1 (0.60) | NPC1RAB9AKMT2AACLYALDH1A1 | |
| SCHEMBL2273182 | 0.83 | PTGS2 (0.66) | NPC1RAB9AKMT2AACLYALDH1A1 | |
| SCHEMBL2267918 | 0.82 | ACLY (0.74) | NPC1RAB9AKMT2AACLYHDAC2 | |
| SCHEMBL2277756 | 0.82 | PTGS2 (0.57) | NPC1RAB9AKMT2AACLYALDH1A1 | |
| SCHEMBL2274927 | 0.81 | ACLY (0.63) | NPC1RAB9AKMT2AACLYALDH1A1 | |
| SCHEMBL2271243 | 0.80 | ADCY1 (0.61) | NPC1RAB9AKMT2AACLYALDH1A1 | |
| SCHEMBL2274216 | 0.78 | RAB9A (0.60) | NPC1RAB9AKMT2AACLYALDH1A1 | |
| SCHEMBL2272939 | 0.77 | ACLY (0.71) | NPC1RAB9AKMT2AACLYMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094829-B | novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO.,LTD. (JP) | 2012-02-08 | — | — | CN | disclosed |
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| CN-101094829-A | Novel anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2007-12-26 | — | — | CN | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |