SCHEMBL2273063

SCHEMBL2273063

O=C(Nc1cc(Oc2ccccc2)ccc1C(=O)O)c1cccc(-n2cccn2)c1

nearest known ligand 0.57

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KAT6A Q92794 2/20 0.50
PYGM P11217 4/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
PYGL P06737 2/20 0.45
PKM P14618 1/20 0.44
SERPINE1 P05121 1/20 0.44
PRSS12 P56730 1/20 0.44
HPSE Q9Y251 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27830397 0.86 KAT6A (0.44) KAT6APYGMMEN1KMT2ANPC1
SCHEMBL2274841 0.85 ACLY (0.54) KAT6AMEN1KMT2APKMSERPINE1
SCHEMBL2271446 0.84 PYGM (0.50) PYGMMEN1KMT2ANPC1RAB9A
SCHEMBL2271350 0.80 PYGM (0.48) KAT6APYGMMEN1KMT2ANPC1
SCHEMBL2271588 0.80 SERPINE1 (0.64) PYGMMEN1KMT2ANPC1RAB9A
SCHEMBL2275060 0.78 AKR1C4 (0.59) PYGMMEN1KMT2ANPC1RAB9A
SCHEMBL2275544 0.78 FABP1 (0.61) PYGMMEN1KMT2ANPC1RAB9A
SCHEMBL2273349 0.77 MEN1 (0.61) PYGMMEN1KMT2ANPC1RAB9A
SCHEMBL2273436 0.77 PYGM (0.70) PYGMMEN1KMT2ANPC1RAB9A
SCHEMBL2269525 0.77 GRIK1 (0.66) PYGMMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101094829-B novel anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO.,LTD. (JP) 2012-02-08 CN disclosed
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 KAT6A 491/4885PYGM 1299/4885MEN1 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.