Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2273285

O=C(Nc1cc(CCc2ccccc2)ccc1C(=O)O)c1cccnc1.O=C(O)C(F)(F)F

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC1 Q13547 5/20 0.51
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ SMN1; SMN2 Q16637 2/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ NPC1 O15118 1/20 0.50
▸ ABCB1 P08183 1/20 0.50
▸ KDM4D Q6B0I6 2/20 0.49
▸ KDM4C Q9H3R0 2/20 0.49
▸ EPHX2 P34913 1/20 0.48
▸ RXFP1 Q9HBX9 1/20 0.47
▸ LMNA P02545 2/20 0.46
▸ HDAC3 O15379 2/20 0.46
▸ HDAC2 Q92769 2/20 0.46
▸ KCNK3 O14649 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ USP2 O75604 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ HPGD P15428 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273286 0.86 ABCB1 (0.49) HDAC1MEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL2275929 0.82 KMT2A (0.62) HDAC1MEN1KMT2AKDM4DKDM4C
SCHEMBL2274939 0.80 PLK1 (0.55) MEN1KMT2ARAB9ANPC1RXFP1
Trifluoroacetic Acid SCHEMBL2273866 0.80 ABCB1 (0.65) HDAC1MEN1KMT2ARAB9ANPC1
SCHEMBL2269100 0.79 PLK1 (0.56) KMT2ARAB9ANPC1
SCHEMBL2270805 0.78 LMNA (0.56) MEN1KMT2ARAB9ANPC1RXFP1
SCHEMBL2270705 0.78 ACLY (0.59) MEN1KMT2ARXFP1MAPT
SCHEMBL2271080 0.77 MEN1 (0.56) HDAC1MEN1KMT2ARAB9ANPC1
SCHEMBL2271236 0.77 PLK1 (0.60) HDAC1MEN1KMT2ARAB9ANPC1
SCHEMBL2272409 0.77 PLK1 (0.63) HDAC1MEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 — — US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 — — US disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 HDAC1 71/4885MEN1 3105/4885KMT2A 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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