Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 7/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.49 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.49 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2274939 | 0.96 | PLK1 (0.55) | PLK1PPARGPPARDPPARANR1H4 | |
| SCHEMBL2270705 | 0.92 | ACLY (0.59) | PLK1PPARGPPARDPPARANR1H4 | |
| SCHEMBL2270805 | 0.90 | LMNA (0.56) | PLK1PPARGPPARDPPARANR1H4 | |
| SCHEMBL2275929 | 0.88 | KMT2A (0.62) | PLK1KMT2AACLYPLK3LTC4S | |
| SCHEMBL2271933 | 0.88 | MEN1 (0.54) | PLK1NPC1RAB9AKMT2APLK3 | |
| SCHEMBL2273288 | 0.87 | AVPR2 (0.49) | PLK1PPARGPPARDPPARANR1H4 | |
| SCHEMBL2270925 | 0.86 | PLK1 (0.57) | PLK1KMT2APLK3LTC4S | |
| SCHEMBL2271421 | 0.86 | DHODH (0.63) | PLK1NPC1RAB9AKMT2AACLY | |
| SCHEMBL2274700 | 0.85 | MEN1 (0.55) | PLK1KMT2AACLYPLK3KCNK2 | |
| SCHEMBL2267959 | 0.85 | PLK1 (0.65) | PLK1NPC1RAB9AKMT2APLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7999132-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-1820795-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240052-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP26, MMP11 | PLK1 4227/4885PPARG 2066/4885PPARD 3684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.