SCHEMBL2274205

SCHEMBL2274205

Cc1ccccc1CCc1ccc(C(=O)O)c(NC(=O)c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.52
PKM P14618 2/20 0.52
KMT2A Q03164 2/20 0.52
MAPT P10636 1/20 0.52
GRIK1 P39086 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
LTC4S Q16873 1/20 0.52
PLK1 P53350 6/20 0.51
PLK3 Q9H4B4 4/20 0.51
HPGD P15428 2/20 0.50
POLB P06746 1/20 0.50
SLC16A3 O15427 3/20 0.48
ALDH1A1 P00352 1/20 0.47
ABCB1 P08183 1/20 0.46
NR3C2 P08235 1/20 0.46
MCL1 Q07820 1/20 0.46
BCL2A1 Q16548 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2365188 0.86 PKM (0.54) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL2275929 0.86 KMT2A (0.62) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL28767741 0.85 MEN1 (0.52) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL2272287 0.84 MEN1 (0.51) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL2273122 0.84 PLK1 (0.57) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL2267959 0.82 PLK1 (0.65) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL2278451 0.82 LTC4S (0.60) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL2271080 0.81 MEN1 (0.56) MEN1PKMKMT2AMAPTGRIK1
SCHEMBL2276177 0.81 SLC16A3 (0.55) PLK1PLK3HPGDPOLBSLC16A3
SCHEMBL2271236 0.81 PLK1 (0.60) MEN1PKMKMT2AMAPTGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 MEN1 3105/4885PKM 2367/4885KMT2A 1669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.