SCHEMBL2276177

SCHEMBL2276177

Cc1ccccc1C(=O)Nc1cc(CCc2ccccc2)ccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC16A3 O15427 1/20 0.55
HPGD P15428 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
RECQL P46063 1/20 0.51
FFAR1 O14842 1/20 0.51
ALDH1A1 P00352 2/20 0.50
POLB P06746 2/20 0.50
KDM4E B2RXH2 1/20 0.50
PLK1 P53350 6/20 0.48
PLK3 Q9H4B4 4/20 0.48
ALOX12 P18054 1/20 0.48
KCNMA1 Q12791 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2274245 0.91 LMNA (0.49) SLC16A3POLBKDM4EPLK1PLK3
SCHEMBL2270880 0.85 ALOX15 (0.60) HPGDRECQLALDH1A1KDM4EPLK1
SCHEMBL2275852 0.84 MEN1 (0.55) SLC16A3HPGDRECQLALDH1A1POLB
SCHEMBL2276434 0.84 RAB9A (0.55) SMN1; SMN2L3MBTL1RECQLALDH1A1POLB
SCHEMBL2270906 0.84 MEN1 (0.56) ALDH1A1KDM4EPLK1PLK3
SCHEMBL2275929 0.83 KMT2A (0.62) PLK1PLK3
SCHEMBL2274146 0.83 PLK1 (0.56) ALDH1A1POLBKDM4EPLK1PLK3
SCHEMBL2267959 0.83 PLK1 (0.65) SLC16A3ALDH1A1PLK1PLK3
SCHEMBL12369770 0.82 KDM4E (0.52) HPGDALDH1A1KDM4EPLK1PLK3
SCHEMBL27970823 0.81 HPGD (0.64) SLC16A3HPGDSMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999132-B2 Anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2011-08-16 US disclosed
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2009-09-24 US disclosed
EP-1820795-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2007-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090240052-A1 NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF MMP13, MMP26, MMP11 SLC16A3 380/4885HPGD 274/4885SMN1; SMN2 3544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.