SCHEMBL2276392

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2272304	0.90	NPC1 (0.55)	DGAT1KCNH2CSF1RDAPK1
	SCHEMBL2275080	0.88	HDAC1 (0.46)	DGAT1CYP3A4SOAT1HDAC3HDAC2
	SCHEMBL2278079	0.86	HDAC2 (0.63)	HDAC3HDAC2KCNH2TRPV1HDAC1
	SCHEMBL2270356	0.86	SERPINE1 (0.48)	DGAT1SERPINE1
	SCHEMBL2274078	0.83	SMN1; SMN2 (0.49)	HDAC3HDAC2KCNH2TRPV1HDAC1
	SCHEMBL2271588	0.78	SERPINE1 (0.64)	SERPINE1
	SCHEMBL1316626	0.77	SIRT6 (0.45)	CSF1RSERPINE1
	SCHEMBL27696834	0.77	MCHR1 (0.60)	TRPV1HDAC1
	SCHEMBL2273868	0.76	NPC1 (0.57)	HDAC3HDAC2SERPINE1HDAC1
	SCHEMBL2272389	0.76	NTRK1 (0.64)	HDAC3HDAC2SERPINE1HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.