SCHEMBL1316626

SCHEMBL1316626

O=C(Nc1cc(Oc2ccccc2)ccc1C(=O)O)c1cc(N2CCCCC2)ccc1O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SIRT6 Q8N6T7 1/20 0.45
NTRK1 P04629 1/20 0.45
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
PNLIP P16233 1/20 0.43
STK39 Q9UEW8 2/20 0.42
CSF1R P07333 1/20 0.42
IP6K1 Q92551 1/20 0.42
SERPINE1 P05121 2/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1315577 0.88 SIRT6 (0.43) SIRT6NTRK1KEAP1NFE2L2PNLIP
SCHEMBL1315669 0.84 ACLY (0.49) IP6K1SERPINE1
Hydrochloric Acid SCHEMBL1316485 0.83 ACLY (0.48) IP6K1SERPINE1
Hydrochloric Acid SCHEMBL1316255 0.83 ACLY (0.48) IP6K1SERPINE1
SCHEMBL12121678 0.83 LRRK2 (0.47) SIRT6KEAP1NFE2L2RXFP1
SCHEMBL1317157 0.82 KEAP1 (0.54) KEAP1NFE2L2RXFP1
SCHEMBL1317606 0.82 DHODH (0.48) KEAP1NFE2L2RXFP1HCAR2
SCHEMBL12118024 0.82 MAPT (0.46) IP6K1SERPINE1
Hydrochloric Acid SCHEMBL1316818 0.80 ACLY (0.49) SERPINE1
SCHEMBL2274195 0.80 PNLIP (0.66) PNLIPSTK39

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102333757-B N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO LTD 2014-11-26 CN disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-8492582-B2 N-acyl anthranilic acid derivative or salt thereof TOYAMA CHEMICAL CO., LTD. (JP) 2013-07-23 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF TOYAMA CHEMICAL CO., LTD. (JP) 2011-11-10 US disclosed
EP-2385036-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF Toyama Chemical Co., Ltd. (JP) 2011-11-09 EP disclosed
WO-2010087430-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF 富山化学工業株式会社 (JP) 2010-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275797-A1 N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF COL14A1, COL2A1, COL1A1 SIRT6 1009/4885NTRK1 4703/4885KEAP1 1080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.