Sugi Predict

Sugi Predict / Compounds / SCHEMBL22764034

SCHEMBL22764034

SCHEMBL22764034

CC1(C)Oc2ccc(C(O)CN3C(=O)CCC3=O)cc2O1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ALOX15 P16050 1/20 0.36
▸ ALOX12 P18054 1/20 0.36
▸ LMNA P02545 2/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ AOC3 Q16853 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ CYP1A2 P05177 2/20 0.33
▸ CYP2C9 P11712 2/20 0.33
▸ CYP2C19 P33261 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ NPC1 O15118 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ KIF11 P52732 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22763936 0.84 TSHR (0.34) TSHRMEN1KMT2ALMNAMAPK1
SCHEMBL22764030 0.84 TSHR (0.34) TSHRMEN1KMT2ALMNAMAPK1
SCHEMBL21709172 0.74 BLM (0.47) TSHRMEN1KMT2AALOX15ALOX12
SCHEMBL22764031 0.73 MAPT (0.50) TSHRMEN1KMT2AALOX12LMNA
SCHEMBL22763956 0.72 RAB9A (0.49) TSHRKMT2AMAPK1ALDH1A1NPC1
SCHEMBL22764035 0.70 NPC1 (0.51) TSHRMEN1KMT2AALOX15ALOX12
SCHEMBL22764032 0.70 AOC3 (0.45) TSHRMEN1KMT2AALOX15ALOX12
SCHEMBL9141282 0.70 ALOX15 (0.50) TSHRMEN1KMT2AALOX15ALOX12
SCHEMBL18500449 0.69 TSHR (0.46) TSHRMEN1KMT2AALOX15ALOX12
SCHEMBL22764033 0.69 ADRB2 (0.50) TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11053227-B2 Process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction and novel synthesis intermediates OLON S.P.A. (IT) 2021-07-06 — — US disclosed
US-20200385366-A1 PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES OLON S.P.A. (IT) 2020-12-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200385366-A1 PROCESS FOR PREPARING INTERMEDIATES FOR THE SYNTHESIS OF OPTICALLY ACTIVE BETA-AMINO ALCOHOLS BY ENZYMATIC REDUCTION AND NOVEL SYNTHESIS INTERMEDIATES ADH1A, ADH1C, ADH5 TSHR 3858/4885MEN1 2751/4885KMT2A 1774/4885
US-11053227-B2 Process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction and novel synthesis intermediates ADH1A, ADH1C, ADH5 TSHR 3858/4885MEN1 2751/4885KMT2A 1774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.