Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 5/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17320566 | 0.90 | CSF1R (0.40) | ACHECA9CYP3A4MAPTCSF1R | |
| SCHEMBL22726982 | 0.85 | CSF1R (0.43) | CA9CSF1RLPLLIPGMEN1 | |
| SCHEMBL16655447 | 0.84 | FPR2 (0.37) | ACHECA9CSF1RLPLLIPG | |
| SCHEMBL28855603 | 0.84 | PDE4A (0.38) | CYP3A4MAPTCSF1RPTGS2LPL | |
| SCHEMBL20600668 | 0.83 | CA1 (0.40) | CA9CYP3A4MAPTCSF1RPTGS2 | |
| SCHEMBL1129266 | 0.81 | LPL (0.45) | CA9CSF1RLPLLIPGALDH1A1 | |
| SCHEMBL24204614 | 0.80 | CSF1R (0.38) | CA9CSF1RLPLLIPGCA1 | |
| SCHEMBL16886087 | 0.80 | CSF1R (0.40) | CA9CYP3A4CSF1RLPLLIPG | |
| SCHEMBL26851003 | 0.80 | PDE5A (0.39) | MAPTALDH1A1HPGDL3MBTL1MEN1 | |
| SCHEMBL26850941 | 0.80 | CA1 (0.39) | CA9CSF1RALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559310-B2 | Reacting a halogen aromatic derivative at a coupling position with a diboron derivative in the presence of a Group VIII metal catalyst and a suitable base for covalently coupling organic compounds | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2003-05-06 | — | — | US | claimed |
| US-20020193604-A1 | Aryl borates | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2002-12-19 | — | — | US | claimed |
| US-20250129016-A1 | PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2025-04-24 | — | — | US | disclosed |
| EP-2935253-B1 | NOVEL HETEROCYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS | ZENITH EPIGENETICS LTD (CA) | 2018-08-01 | — | — | EP | disclosed |
| US-9861637-B2 | Heterocyclic compounds as bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2018-01-09 | — | — | US | disclosed |
| US-20170143731-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS | ZENITH EPIGENETICS LTD. | 2017-05-25 | — | — | US | disclosed |
| US-9598367-B2 | Heterocyclic compounds as bromodomain inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2017-03-21 | — | — | US | disclosed |
| US-20160130228-A1 | Novel Heterocyclic Compounds as Bromodomain Inhibitors | ZENITH EPIGENETICS LTD. (CA) | 2016-05-12 | — | — | US | disclosed |
| US-9290435-B2 | Molecular glass of spirofluorene derivative, preparation method thereof and use thereof in photo-etching | Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences (CN) | 2016-03-22 | — | — | US | disclosed |
| US-9271978-B2 | Heterocyclic compounds as bromodomain inhibitors | ZENITH EPIGENETICS CORP. (CA) | 2016-03-01 | — | — | US | disclosed |
| US-20150353468-A1 | MOLECULAR GLASS OF SPIROFLUORENE DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN PHOTO-ETCHING | Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences (CN) | 2015-12-10 | — | — | US | disclosed |
| US-8530689-B2 | Processes for the preparation of biphenyl compounds | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-09-10 | — | — | US | disclosed |
| US-20110207957-A1 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110207957-A1 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110207957-A1 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-08-25 | — | — | US | disclosed |
| WO-2009137322-A2 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-11-12 | — | — | WO | disclosed |
| US-7122694-B2 | Hydroboronation process | BORON MOLECULAR PTY LIMITED (AU) | 2006-10-17 | — | — | US | disclosed |
| US-20040133028-A1 | Hydroboronation process | COMMONWEALTH SCIENTIFIC | 2004-07-08 | — | — | US | disclosed |
| EP-1127060-B1 | HYDROBORONATION PROCESS | COMMW SCIENT IND RES ORG (AU) | 2004-04-07 | — | — | EP | disclosed |
| US-6680401-B1 | BORON COMPOUNDS SUCH AS 4-(METHOXYMETHYL)-1,3,2-DIOXABOROLANE, USED AS COUPLERS OR CHEMICAL INTERMEDIATES FOR DRUGS, PESTICIDES OR IN COMBINATORIAL CHEMISTRY | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2004-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130228-A1 | Novel Heterocyclic Compounds as Bromodomain Inhibitors | BRD4, BRDT, BRD3 | ACHE 4706/4885CA9 4802/4885CYP3A4 4590/4885 |
| US-20110207957-A1 | PROCESSES FOR THE PREPARATION OF BIPHENYL COMPOUNDS | C1S, BAX, C9 | ACHE 2994/4885CA9 2704/4885CYP3A4 41/4885 |
| US-20020193604-A1 | Aryl borates | BRD4, ABL1, BRD3 | ACHE 2773/4885CA9 643/4885CYP3A4 57/4885 |
| US-20170143731-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS BROMODOMAIN INHIBITORS | BRD4, BRDT, BRD3 | ACHE 4706/4885CA9 4802/4885CYP3A4 4590/4885 |
| US-20040133028-A1 | Hydroboronation process | ALKBH3, HPD, HVCN1 | ACHE 4587/4885CA9 928/4885CYP3A4 80/4885 |
| US-20250129016-A1 | PHOTOREDOX METHODS FOR RADIOCYANATION OF ARENES AND USE THEREOF | RCC2, PPOX, FTO | ACHE 3507/4885CA9 54/4885CYP3A4 110/4885 |
| US-20150353468-A1 | MOLECULAR GLASS OF SPIROFLUORENE DERIVATIVE, PREPARATION METHOD THEREOF AND USE THEREOF IN PHOTO-ETCHING | PDGFRA, ARHGEF12, GLI2 | ACHE 4780/4885CA9 2692/4885CYP3A4 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.