SCHEMBL22840928

SCHEMBL22840928

C=CC(=O)OC(C)(C)c1cccc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LMNA P02545 2/20 0.38
KIF11 P52732 3/20 0.36
PARP1 P09874 1/20 0.35
MEN1 O00255 2/20 0.35
HPGD P15428 2/20 0.35
KMT2A Q03164 2/20 0.35
PTPN5 P54829 1/20 0.34
KCNK3 O14649 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
EDNRB P24530 1/20 0.34
EDNRA P25101 1/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
EGFR P00533 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22829480 0.90 ESR1 (0.35) LMNAKMT2A
SCHEMBL4596471 0.82 ALDH1A1 (0.48) KMT2AHTT
SCHEMBL29331099 0.81 TSHR (0.33)
Ethane SCHEMBL28624063 0.80 ALDH1A1 (0.47) KMT2AHTT
SCHEMBL20494345 0.79 THRB (0.37) TP53MEN1HPGDKMT2AHTT
SCHEMBL22829479 0.79 RXRA (0.32) KMT2A
SCHEMBL22851799 0.79 CYP2C19 (0.34)
SCHEMBL25916385 0.78 LMNA (0.41) LMNAKIF11PARP1MEN1HPGD
SCHEMBL3126665 0.77 ACHE (0.38) TP53TDP1LMNAKIF11PTPN5
SCHEMBL16181793 0.75 CYP2C9 (0.37) TDP1LMNAMEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3757175-A1 RADIATION CURABLE INKJET INK FOR ALKALINE ETCHING OR PLATING APPLICATIONS AGFA-GEVAERT NV (BE) 2020-12-30 EP disclosed