SCHEMBL2289089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2289558	0.81	ALDH1A1 (0.56)	KDM4EALDH1A1HPGDHSD17B10TSHR
	SCHEMBL2570498	0.78	ALDH1A1 (0.57)	KDM4EALDH1A1HPGDHSD17B10TSHR
	SCHEMBL2283588	0.76	STS (0.47)	KDM4EALDH1A1HPGDHSD17B10TSHR
	SCHEMBL2569140	0.72	ALDH1A1 (0.50)	KDM4EALDH1A1HPGDHSD17B10TSHR
	SCHEMBL6159067	0.72	HTR1D (0.39)	CYP1A2
	SCHEMBL14526308	0.71	DGAT1 (0.40)	CYP1A2
	SCHEMBL14526312	0.70	HTR1D (0.34)	ALDH1A1MAPTDRD2DRD3
	SCHEMBL14526545	0.69	CYP3A4 (0.39)	CYP1A2
	SCHEMBL6157618	0.68	HTR1D (0.36)	ALDH1A1MAPTDRD2DRD3
	SCHEMBL14526306	0.67	CYP2C9 (0.33)	ALDH1A1MAPTMAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.