Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354448 | 0.75 | ADRB2 (0.53) | ADRB2ADRB1ADRB3L3MBTL1RAB9A | |
| SCHEMBL22891783 | 0.71 | TAS2R14 (0.40) | HTR7RAB9ANPC1ALDH1A1 | |
| SCHEMBL19321862 | 0.69 | HTR7 (0.49) | HTR7L3MBTL1RXRARAB9ANPC1 | |
| SCHEMBL22891790 | 0.67 | HTT (0.44) | RAB9AALDH1A1MAPT | |
| SCHEMBL29670040 | 0.67 | HTT (0.44) | RAB9AALDH1A1MAPT | |
| SCHEMBL16785739 | 0.67 | RAB9A (0.49) | ADRB2ADRB1ADRB3HTR7CYP2C9 | |
| SCHEMBL7433225 | 0.67 | ADRB2 (0.54) | ADRB2ADRB1ADRB3HTR7RXRA | |
| SCHEMBL18862636 | 0.66 | MAPK1 (0.55) | ADRB2ADRB1ADRB3L3MBTL1RXRA | |
| SCHEMBL822797 | 0.65 | NPC1 (0.57) | ADRB2ADRB1ADRB3L3MBTL1RAB9A | |
| SCHEMBL19317285 | 0.63 | HTR7 (0.49) | HTR7RXRARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007474-A1 | PHENYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | CURA THERAPEUTICS, LLC (US) | 2021-01-14 | — | — | WO | disclosed |