Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670040 | 1.00 | HTT (0.44) | HTTHDAC3HDAC11HDAC8HDAC6 | |
| SCHEMBL29669997 | 0.79 | NPSR1 (0.49) | HTTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22891786 | 0.79 | NPSR1 (0.49) | HTTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL22891783 | 0.69 | TAS2R14 (0.40) | HTTMEN1KMT2AGAAHPGD | |
| SCHEMBL19354448 | 0.68 | ADRB2 (0.53) | MAPTKMT2ANPSR1KDM4ERAB9A | |
| SCHEMBL22891791 | 0.67 | ADRB2 (0.34) | MAPTALDH1A1RAB9A | |
| SCHEMBL19321862 | 0.67 | HTR7 (0.49) | HTTMAPTMEN1KMT2AGAA | |
| SCHEMBL7433225 | 0.65 | ADRB2 (0.54) | ALDH1A1KDM4E | |
| SCHEMBL30786693 | 0.64 | CES2 (0.61) | HDAC3MAPTMEN1KMT2AHPGD | |
| SCHEMBL1994068 | 0.64 | CES2 (0.61) | HDAC3MAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021007474-A1 | PHENYL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | CURA THERAPEUTICS, LLC (US) | 2021-01-14 | — | — | WO | disclosed |