Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25065427 | 1.00 | KCNH2 (0.47) | KCNH2HTR2ASIGMAR1PTGESALOX5 | |
| SCHEMBL7797335 | 0.85 | CSNK1E (0.44) | KCNH2HTR2APTGESALOX5PPARG | |
| SCHEMBL9574239 | 0.81 | KCNH2 (0.48) | KCNH2HTR2ASIGMAR1PTGESALOX5 | |
| SCHEMBL25065345 | 0.81 | DNM1 (0.45) | — | |
| SCHEMBL27456433 | 0.79 | SIGMAR1 (0.47) | KCNH2HTR2ASIGMAR1 | |
| SCHEMBL3033446 | 0.79 | KCNH2 (0.44) | KCNH2HTR2ASIGMAR1CSNK1E | |
| SCHEMBL25065426 | 0.78 | FAAH (0.49) | — | |
| SCHEMBL22922952 | 0.78 | FAAH (0.49) | — | |
| SCHEMBL2670017 | 0.76 | KCNH2 (0.59) | KCNH2HTR2ASIGMAR1 | |
| SCHEMBL469641 | 0.76 | KCNH2 (0.59) | KCNH2HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210023106-A1 | TOLL-LIKE RECEPTOR LIGANDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210023106-A1 | TOLL-LIKE RECEPTOR LIGANDS | TLR1, TLR4, TLR6 | KCNH2 4281/4885HTR2A 1835/4885SIGMAR1 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.