Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ALPG | P10696 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409836 | 0.96 | CES2 (0.54) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL29377967 | 0.94 | CES2 (0.56) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL896769 | 0.94 | CES2 (0.56) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL29433447 | 0.90 | AKR1C3 (0.61) | LMNASMN1; SMN2HPGDALDH1A1AKR1C3 | |
| SCHEMBL333008 | 0.90 | AKR1C3 (0.61) | LMNASMN1; SMN2HPGDALDH1A1AKR1C3 | |
| SCHEMBL27873928 | 0.88 | AKR1C3 (0.65) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL10759830 | 0.88 | CES2 (0.62) | LMNAHPGDALDH1A1AKR1C3NPC1 | |
| Benzene SCHEMBL28318261 | 0.86 | AKR1C3 (0.61) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL251921 | 0.86 | ALDH1A1 (0.70) | LMNASMN1; SMN2HPGDALPGALDH1A1 | |
| SCHEMBL7940606 | 0.86 | ALDH1A1 (0.70) | LMNASMN1; SMN2HPGDALPGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815937-B2 | Process for preparing a poly(aryl ether ketone) using a high purity 4,4′-difluorobenzophenone | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2017-11-14 | — | — | US | claimed |
| US-20160145386-A1 | PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'- DIFLUOROBENZOPHENONE | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2016-05-26 | — | — | US | claimed |
| US-9133111-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2015-09-15 | — | — | US | claimed |
| US-20140221595-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | SOLVAY ADVANCED POLYMERS, LLC (US) | 2014-08-07 | — | — | US | claimed |
| US-8710171-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2014-04-29 | — | — | US | claimed |
| US-20110213115-A1 | Process for preparing a poly(aryl ether ketone) using a high purity 4,4'-difluorobenzophenone | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-09-01 | — | — | US | claimed |
| US-20110201775-A1 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-08-18 | — | — | US | claimed |
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2018-07-17 | — | — | US | disclosed |
| US-9815937-B2 | Process for preparing a poly(aryl ether ketone) using a high purity 4,4′-difluorobenzophenone | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2017-11-14 | — | — | US | disclosed |
| US-9765185-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20160145385-A1 | METHOD FOR THE MANUFACTURE OF POLY(ARYL ETHER KETONE)S IN THE PRESENCE OF SODIUM CARBONATE | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2016-05-26 | — | — | US | disclosed |
| US-20160145386-A1 | PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'- DIFLUOROBENZOPHENONE | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2016-05-26 | — | — | US | disclosed |
| US-20150344418-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | SOLVAY ADVANCED POLYMERS, LLC (US) | 2015-12-03 | — | — | US | disclosed |
| US-9175136-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2015-11-03 | — | — | US | disclosed |
| US-9133111-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140221595-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | SOLVAY ADVANCED POLYMERS, LLC (US) | 2014-08-07 | — | — | US | disclosed |
| US-8710171-B2 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20110213095-A1 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110213115-A1 | Process for preparing a poly(aryl ether ketone) using a high purity 4,4'-difluorobenzophenone | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-09-01 | — | — | US | disclosed |
| US-20110201775-A1 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | SOLVAY ADVANCED POLYMERS, L.L.C. (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023692-B2 | Method for the manufacture of poly(aryl ether ketone)s in the presence of sodium carbonate | PKM, KCNK10, KCNK9 | LMNA 1173/4885SMN1; SMN2 3155/4885HPGD 4652/4885 |
| US-20110201775-A1 | High purity diphenyl sulfone, preparation and use thereof for the preparation of a poly(aryletherketone) | DHPS, PKM, PCBP1 | LMNA 1322/4885SMN1; SMN2 740/4885HPGD 3118/4885 |
| US-20140221595-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | DHPS, PKM, PCBP1 | LMNA 1659/4885SMN1; SMN2 335/4885HPGD 3067/4885 |
| US-20150344418-A1 | HIGH PURITY DIPHENYL SULFONE, PREPARATION AND USE THEREOF FOR THE PREPARATION OF A POLY(ARYLETHERKETONE) | DHPS, PKM, PCBP1 | LMNA 1659/4885SMN1; SMN2 335/4885HPGD 3067/4885 |
| US-20160145386-A1 | PROCESS FOR PREPARING A POLY(ARYL ETHER KETONE) USING A HIGH PURITY 4,4'- DIFLUOROBENZOPHENONE | HNF4A, CUL4B, CUL4A | LMNA 4016/4885SMN1; SMN2 4554/4885HPGD 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.