Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.48 |
| ▸ | THRA | P10827 | 11/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818059 | 0.81 | RORC (0.70) | THRBTHRARORC | |
| SCHEMBL22959352 | 0.78 | THRB (0.52) | THRBTHRARORC | |
| SCHEMBL8892802 | 0.77 | THRB (0.48) | THRBTHRARORC | |
| SCHEMBL22959367 | 0.76 | THRB (0.49) | THRBTHRARORC | |
| SCHEMBL2044734 | 0.75 | THRA (0.71) | THRBTHRA | |
| SCHEMBL6512367 | 0.74 | THRB (0.63) | THRBTHRARORC | |
| SCHEMBL8893247 | 0.73 | THRB (0.57) | THRBTHRARORC | |
| SCHEMBL5324895 | 0.73 | THRB (0.54) | THRBTHRARORC | |
| SCHEMBL22959261 | 0.72 | THRB (0.70) | THRBTHRARORC | |
| SCHEMBL11031583 | 0.72 | MAPT (0.48) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |