Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.49 |
| ▸ | RORC | P51449 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962647 | 0.83 | ALDH1A1 (0.40) | THRBTHRAMEN1MAPTKMT2A | |
| SCHEMBL22959143 | 0.81 | ALDH1A1 (0.39) | THRBRORCTHRAMEN1MAPT | |
| SCHEMBL5324856 | 0.81 | ALDH1A1 (0.45) | THRBRORCTHRAMEN1MAPT | |
| SCHEMBL6818059 | 0.81 | RORC (0.70) | THRBRORCTHRA | |
| SCHEMBL3228597 | 0.80 | TDP1 (0.50) | MEN1KMT2ALMNAALDH1A1NPBWR1 | |
| SCHEMBL3702751 | 0.79 | THRB (0.45) | THRBRORCTHRAKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL29965433 | 0.78 | ALDH1A1 (0.52) | THRBMEN1MAPTKMT2ALMNA | |
| SCHEMBL12312745 | 0.76 | THRB (0.58) | THRBRORCTHRAALDH1A1 | |
| SCHEMBL3221389 | 0.76 | THRB (0.57) | THRBRORCTHRAMAPTGAA | |
| SCHEMBL22959351 | 0.76 | THRB (0.48) | THRBRORCTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220306630-A1 | AGONISTS OF ROR GAMMAt | BRISTOL MYERS SQUIBB CO (US) | 2022-09-29 | — | — | US | disclosed |
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |
| WO-2021026179-A1 | AGONISTS OF ROR GAMMAt | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220306630-A1 | AGONISTS OF ROR GAMMAt | RORB, RORA, RORC | THRB 44/4885RORC 3/4885THRA 58/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.