Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22961956 | 0.83 | HDAC4 (0.42) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL22962032 | 0.81 | HDAC4 (0.42) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL785870 | 0.81 | CTSS (0.56) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL19734820 | 0.79 | KMT2A (0.48) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL28737415 | 0.79 | KMT2A (0.48) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL22962320 | 0.79 | HDAC4 (0.43) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL7513684 | 0.77 | CTSK (0.51) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL8133237 | 0.77 | HDAC4 (0.52) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL8133234 | 0.77 | HDAC4 (0.52) | HDAC4HDAC1HDAC6CTSSCTSK | |
| SCHEMBL25174673 | 0.76 | HDAC4 (0.58) | HDAC4HDAC1HDAC6CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092091-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE LIGANDS | Humanwell Pharmaceutical US | 2025-03-20 | — | — | US | disclosed |
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | YICHANG HUMANWELL PHARMACEUTICALS CO., LTD. (CN) | 2021-02-11 | — | — | US | disclosed |
| WO-2021026492-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | Humanwell Pharmaceutical US (US) | 2021-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092091-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE LIGANDS | OPRK1, OPRL1, OPRD1 | HDAC4 3932/4885HDAC1 4164/4885HDAC6 2336/4885 |
| US-20210040150-A1 | KAPPA OPIOID RECEPTOR PEPTIDE AMIDE AGONISTS | OPRK1, OPRL1, OPRD1 | HDAC4 3969/4885HDAC1 4299/4885HDAC6 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.