Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965191 | 0.88 | PTGDR2 (0.47) | LMNAKDM4ERECQLTP53MAPT | |
| SCHEMBL22965156 | 0.83 | TBXA2R (0.46) | KMT2AHDAC6RECQLL3MBTL1 | |
| SCHEMBL7522351 | 0.81 | ALDH1A1 (0.58) | LMNAHDAC6RECQLTP53MAPT | |
| SCHEMBL23779995 | 0.81 | KDM4E (0.60) | LMNAKDM4EKMT2AHDAC6RECQL | |
| SCHEMBL540895 | 0.75 | TP53 (0.65) | LMNAKDM4ERECQLTP53MAPT | |
| SCHEMBL540973 | 0.74 | TP53 (0.59) | LMNARECQLTP53MAPTSMN1; SMN2 | |
| SCHEMBL22965267 | 0.72 | FAAH (0.40) | RECQLSMN1; SMN2ALDH1A1 | |
| SCHEMBL22965215 | 0.72 | LMNA (0.60) | LMNAKDM4EKMT2AHDAC6TP53 | |
| SCHEMBL540852 | 0.71 | LMNA (0.59) | LMNAKDM4EKMT2AHDAC6TP53 | |
| SCHEMBL6809443 | 0.71 | RAB9A (0.50) | LMNAHDAC6TP53SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |