Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22965254 | 0.88 | LMNA (0.48) | RECQLSMN1; SMN2POLBL3MBTL1TP53 | |
| SCHEMBL22965267 | 0.84 | FAAH (0.40) | FAAHRECQLSMN1; SMN2GAA | |
| SCHEMBL7745965 | 0.80 | SMN1; SMN2 (0.58) | PTGDR2FAAHRECQLSMN1; SMN2POLB | |
| SCHEMBL7741979 | 0.79 | FAAH (0.56) | PTGDR2FAAHRECQLSMN1; SMN2POLB | |
| SCHEMBL7522351 | 0.78 | ALDH1A1 (0.58) | RECQLSMN1; SMN2TP53LMNAMAPT | |
| SCHEMBL540973 | 0.77 | TP53 (0.59) | RECQLSMN1; SMN2POLBL3MBTL1TP53 | |
| SCHEMBL22965212 | 0.77 | PTGDR2 (0.59) | PTGDR2FAAHTP53KDM4EHSD17B10 | |
| SCHEMBL22965246 | 0.76 | PTGDR2 (0.54) | PTGDR2FAAHRECQLSMN1; SMN2POLB | |
| SCHEMBL3008241 | 0.76 | MAPT (0.54) | PTGDR2FAAHRECQLSMN1; SMN2POLB | |
| SCHEMBL22965231 | 0.75 | TSHR (0.59) | PTGDR2FAAHRECQLSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021023796-A1 | COMPOSITIONS FOR TRANSFECTING A NUCLEIC ACID MOLECULE INTO A CELL COMPRISING HETEROCYCLIC COMPOUNDS GRAFTED TO A CATIONIC POLYMER, AND THEIR APPLICATIONS | POLYPLUS TRANSFECTION (FR) | 2021-02-11 | — | — | WO | disclosed |