Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16055751 | 0.86 | NPBWR1 (0.41) | KIF11MAPK1NFE2L2NPBWR1CYP1A2 | |
| SCHEMBL5897973 | 0.85 | PTPN5 (0.41) | RAPGEF4KIF11NFE2L2CES2 | |
| SCHEMBL2013705 | 0.80 | RXRA (0.33) | MAPK1TSHRPDE2ACES2 | |
| SCHEMBL8078153 | 0.79 | KIF11 (0.43) | NOTUMKIF11TSHRCYP1A2CYP3A4 | |
| SCHEMBL1370057 | 0.78 | KIF11 (0.47) | KIF11MAPK1TSHRNPBWR1MAPT | |
| SCHEMBL7138582 | 0.77 | ACHE (0.36) | TSHRCYP1A2 | |
| SCHEMBL2204411 | 0.76 | NOTUM (0.43) | NOTUMKIF11MAPK1TSHRCES2 | |
| SCHEMBL1690372 | 0.76 | SMN1; SMN2 (0.34) | KIF11MAPK1LMNAPDE2ACYP1A2 | |
| SCHEMBL28008356 | 0.76 | PSEN1 (0.43) | CYP3A4 | |
| SCHEMBL11565582 | 0.76 | RAPGEF4 (0.31) | RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110200925-A1 | IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2011-08-18 | — | — | US | disclosed |